Musholt Thomas J
Sektion Endokrine Chirurgie, Klinik für Allgemein‑, Viszeral- und Transplantationschirurgie, Universitätsmedizin Mainz, Langenbeckstr. 1, 55101, Mainz, Deutschland.
Chirurg. 2020 Dec;91(12):1030-1037. doi: 10.1007/s00104-020-01262-z.
Advanced thyroid carcinomas with infiltration of the aerodigestive tract are rare but are responsible for approximately 50% of the tumor-specific mortality. Due to impending and frequently life-threatening local complications and in the absence of promising therapeutic alternatives, a resection in curative or palliative intention is indicated if the local tumor is resectable. The resection and especially reconstruction of the trachea represent an extraordinary surgical challenge, require an individualized approach as well as exact knowledge of tracheal resection techniques. The decision for surgery in general, the selection of adequate resection and reconstruction strategies as well as the perioperative management should be accompanied by a particularly experienced interdisciplinary team.
侵犯气道消化道的晚期甲状腺癌虽罕见,但约占肿瘤特异性死亡的50%。由于存在即将发生且常危及生命的局部并发症,且缺乏有效的治疗选择,若局部肿瘤可切除,则应行根治性或姑息性切除。气管切除尤其是重建是一项极具挑战性的手术,需要个体化方法以及对气管切除技术的精确了解。一般而言,手术决策、合适的切除与重建策略选择以及围手术期管理应由经验丰富的多学科团队共同参与。