Department of Dermatology and Venereology, University Medical Center, Rostock, Germany.
J Dtsch Dermatol Ges. 2020 Aug;18(8):867-880. doi: 10.1111/ddg.14207. Epub 2020 Aug 9.
Besides conditions such as scabies and hypersensitivity to house dust mites, other diseases caused by mites and caterpillars tend to be more uncommon in everyday practice. Nevertheless, there is a broad spectrum of medically relevant disorders associated with these arthropods. Mites may act as parasites that infect or colonize the skin (e.g., scabies, pseudoscabies, demodicosis) or they may pierce the host's skin and feed on tissue fluid and blood (trombiculosis). In the latter case, they also play a role as vectors transmitting Orientia tsutsugamushi, the pathogen that causes Tsutsugamushi fever. In addition to house dust mites, storage mites, too, are characterized by their allergenic potential. The terms erucism and lepidopterism are used for the various diseases caused by caterpillars and moths. Both terms are not used consistently. With respect to pathogenesis, various mechanisms have been described, including type I and type IV hypersensitivity as well as irritant and toxin-induced reactions. In Germany, skin reactions following exposure to the hairs of oak processionary caterpillars are particularly common. Extracutaneous manifestations including nausea, vomiting, hemorrhage, arthropathy or even life-threatening reactions have been reported in association with certain exotic species. Some species act as parasites by feeding on blood or tears. As natural silk can cause immediate and delayed-type hypersensitivity reactions, workers in the silk industry may develop allergic asthma, rhinitis, or conjunctivitis. Consumption of silkworm pupae is associated with the risk of food allergy.
除了疥疮和对屋尘螨过敏等情况外,由螨虫和毛毛虫引起的其他疾病在日常实践中往往较为少见。然而,与这些节肢动物相关的具有广泛医学意义的疾病种类繁多。螨虫可能作为寄生虫感染或定殖于皮肤(例如,疥疮、假性疥疮、蠕形螨病),也可能刺穿宿主的皮肤并吸食组织液和血液(恙螨病)。在后一种情况下,它们还充当传播恙虫病东方体的媒介,该病原体可引起恙虫病。除了屋尘螨,储存螨也具有致敏潜能。毛毛虫和蛾子引起的各种疾病分别被称为鳞翅目昆虫病和毛翅目昆虫病。这两个术语的使用并不一致。就发病机制而言,已经描述了多种机制,包括 I 型和 IV 型超敏反应以及刺激性和毒素诱导的反应。在德国,暴露于橡树行军毛虫的毛发后出现皮肤反应的情况尤其常见。与某些外来物种相关的还报告了包括恶心、呕吐、出血、关节病甚至危及生命的反应等皮肤外表现。有些物种通过吸食血液或眼泪来寄生。由于天然丝可引起即刻和迟发型超敏反应,丝绸行业的工人可能会发展为过敏性哮喘、鼻炎或结膜炎。食用蚕蛹与食物过敏的风险相关。