van Hage-Hamsten M, Johansson S G
Department of Clinical Immunology, Karolinska Institute, Karolinska Hospital, Stockholm, Sweden.
Exp Appl Acarol. 1992 Nov;16(1-2):117-28. doi: 10.1007/BF01201495.
The interest in allergy to storage mites has increased over the past few years. Storage mites feed on a variety of substances and they can be found in many different products such as grain, flour, hay and straw, but also in house dust samples. The more common genera are Lepidoglyphus, Tyrophagus, Glycyphagus, Acarus and Blomia. Several species of storage mites have been shown to cause IgE-mediated sensitization among rural workers, who to a varying extent develop asthma, rhinitis or conjunctivitis when exposed to barn dust. However, a number of studies have reported on sensitization to storage mites also among urban people, indicating that sensitization is not restricted to individuals with occupational exposure. Regarding the allergenic relationship between storage mites and house dust mites, there appears to be a limited allergenic cross-reactivity between the two species. However, both species also possess their own unique allergens. Further research on identification and characterization of storage mite allergens and their cross-reactivity is required to understand the complexity of epitopes and allergens.
在过去几年里,人们对仓储螨过敏的关注度有所增加。仓储螨以多种物质为食,在许多不同产品中都能发现它们的踪迹,如谷物、面粉、干草和稻草,在室内灰尘样本中也能找到。比较常见的属有鳞翅螨属、食酪螨属、嗜甜螨属、粉螨属和柏氏禽刺螨属。已有研究表明,几种仓储螨会导致农村工人发生IgE介导的致敏反应,这些工人在接触谷仓灰尘时,会不同程度地患上哮喘、鼻炎或结膜炎。然而,也有多项研究报告称城市人群中也存在对仓储螨的致敏现象,这表明致敏并不局限于有职业暴露的个体。关于仓储螨和屋尘螨之间的变应原关系,这两个物种之间似乎存在有限的变应原交叉反应。然而,这两个物种也都有各自独特的变应原。需要进一步研究仓储螨变应原的鉴定和特征及其交叉反应,以了解表位和变应原的复杂性。