一项比较局部用卡替洛尔和安慰剂对眼压影响的双交叉试验。
A double-crossover trial comparing the effects of topical carteolol and placebo on intraocular pressure.
作者信息
Duff G R, Graham P A
机构信息
Department of Ophthalmology, University Hospital of Wales.
出版信息
Br J Ophthalmol. 1988 Jan;72(1):27-8. doi: 10.1136/bjo.72.1.27.
Abstract
The effect of topical carteolol 2% on the intraocular pressures of 12 patients suspected of having glaucoma was measured in a double-crossover trial of six weeks' duration. Carteolol produced a significant reduction in intraocular pressure (p less than or equal to 0.001), when compared with placebo. This represented reductions of 11% and 14%, after one and two weeks of treatment.
摘要
在一项为期六周的双交叉试验中，测量了2%噻吗洛尔滴眼液对12名疑似青光眼患者眼压的影响。与安慰剂相比，噻吗洛尔使眼压显著降低（p≤0.001）。治疗一周和两周后，眼压分别降低了11%和14%。
相似文献
1
A double-crossover trial comparing the effects of topical carteolol and placebo on intraocular pressure.一项比较局部用卡替洛尔和安慰剂对眼压影响的双交叉试验。
Br J Ophthalmol. 1988 Jan;72(1):27-8. doi: 10.1136/bjo.72.1.27.
2
The 12-hour control of intraocular pressure on carteolol 2% twice daily.每日两次使用2%的卡替洛尔对眼压进行12小时的控制。
Br J Ophthalmol. 1988 Dec;72(12):890-1. doi: 10.1136/bjo.72.12.890.
3
A double-masked comparison of carteolol and timolol in ocular hypertension.卡替洛尔与噻吗洛尔治疗高眼压症的双盲对照研究。
Am J Ophthalmol. 1988 Feb 15;105(2):150-4. doi: 10.1016/0002-9394(88)90178-x.
4
A double-masked crossover study comparing the effects of carteolol 1% and 2% on intra-ocular pressure.一项比较1%和2%卡替洛尔对眼压影响的双盲交叉研究。
Acta Ophthalmol (Copenh). 1987 Oct;65(5):618-21. doi: 10.1111/j.1755-3768.1987.tb07052.x.
5
A comparison of the ocular hypotensive efficacy and systemic safety of 0.5% levobunolol and 2% carteolol.0.5%左布诺洛尔与2%卡替洛尔的降眼压疗效及全身安全性比较。
Ophthalmologica. 1994;208(1):32-6. doi: 10.1159/000310446.
6
[Tolerance and pharmacologic effectiveness of antiglaucoma eyedrops].
Klin Monbl Augenheilkd. 1986 Jun;188(6):573-5. doi: 10.1055/s-2008-1050718.
7
[Efficacy and safety of long-acting carteolol 1% once daily. A double-masked, randomized study].[1%长效卡替洛尔每日一次的疗效与安全性。一项双盲随机研究]
J Fr Ophtalmol. 2003 Feb;26(2):131-6.
8
[Carteolol: general practice-oriented assessment of the effectiveness and tolerance of a new beta-blocker in the treatment of glaucoma].[卡替洛尔：一种新型β受体阻滞剂治疗青光眼的有效性和耐受性的全科医学导向评估]
Klin Monbl Augenheilkd. 1988 Mar;192(3):248-51. doi: 10.1055/s-2008-1050111.
9
Carteolol: preliminary study on ocular pressure-reducing action.卡替洛尔：眼压降低作用的初步研究。
Ophthalmologica. 1983;187(3):171-3. doi: 10.1159/000309320.
引用本文的文献
1
The 12-hour control of intraocular pressure on carteolol 2% twice daily.每日两次使用2%的卡替洛尔对眼压进行12小时的控制。
Br J Ophthalmol. 1988 Dec;72(12):890-1. doi: 10.1136/bjo.72.12.890.
2
Ocular carteolol. A review of its pharmacological properties, and therapeutic use in glaucoma and ocular hypertension.噻吗洛尔滴眼液。其药理特性及在青光眼和高眼压症治疗中的应用综述。
Drugs Aging. 1992 Jan-Feb;2(1):58-77. doi: 10.2165/00002512-199202010-00007.
3
Ocular beta-blockers in glaucoma management. Clinical pharmacological aspects.青光眼治疗中的眼部β受体阻滞剂。临床药理学方面。
Drugs Aging. 1992 May-Jun;2(3):208-21. doi: 10.2165/00002512-199202030-00005.
本文引用的文献
1
[Ocular hypotensive effects of carteolol hydrochloride in primary open-angle glaucoma and ocular hypertensive patients. A double-masked cross-over study for the determination of concentrations optimal for the clinical use (author's transl)].盐酸卡替洛尔对原发性开角型青光眼和高眼压症患者的降眼压作用。一项双盲交叉研究以确定临床使用的最佳浓度（作者译）
Nippon Ganka Gakkai Zasshi. 1981;85(7):798-804.
2
[Effects of beta-blocking agent carteolol on healthy volunteers and glaucoma patients (author's transl)].β受体阻滞剂卡替洛尔对健康志愿者和青光眼患者的影响（作者译）
Nippon Ganka Gakkai Zasshi. 1981 Jan;85(1):57-66.
3
Selective perimetry for glaucomatous defects in ocular hypertension.对高眼压症患者青光眼性缺损进行选择性视野检查。
Arch Ophthalmol. 1972 May;87(5):518-24. doi: 10.1001/archopht.1972.01000020520005.
4
The two-period cross-over clinical trial.两阶段交叉临床试验。
Br J Clin Pharmacol. 1979 Jul;8(1):7-20. doi: 10.1111/j.1365-2125.1979.tb05903.x.
Zotero 插件