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[卡替洛尔:一种新型β受体阻滞剂治疗青光眼的有效性和耐受性的全科医学导向评估]

[Carteolol: general practice-oriented assessment of the effectiveness and tolerance of a new beta-blocker in the treatment of glaucoma].

作者信息

Schnaudigel O E, Becker H, Fuchs H B

机构信息

Augenklinik der Johann Wolfgang Goethe-Universität Frankfurt/Main.

出版信息

Klin Monbl Augenheilkd. 1988 Mar;192(3):248-51. doi: 10.1055/s-2008-1050111.

Abstract

During an open multicenter field study the new beta-blocking agent Carteolol, in 1% and 2% solution, proved to be effective and safe in the treatment of 178 patients suffering from glaucoma. On average, IOP was lowered by 5.8 to 18.7 mm Hg in nontreated and by 4.8 to 17.8 mm Hg in pretreated patients. In more than 90% of the cases both the patients and the investigators judged the treatment to be good, or better than the previous therapy. Side affects occurred in less than 3% of the cases.

摘要

在一项开放性多中心实地研究中,新型β受体阻滞剂噻吗洛尔1%和2%溶液被证明在治疗178例青光眼患者时有效且安全。未经治疗的患者眼压平均降低5.8至18.7毫米汞柱,接受过预处理的患者眼压平均降低4.8至17.8毫米汞柱。在超过90%的病例中,患者和研究人员都认为治疗效果良好,或优于先前的治疗方法。副作用发生率低于3%。

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