Matsuo Takashi, Moriuchi Takefumi, Iso Naoki, Hasegawa Takashi, Miyata Hironori, Maruta Michio, Mitsutake Tsubasa, Yamaguchi Yoichi, Tabira Takayuki, Higashi Toshio
Unit of Medical Sciences, Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki.
Faculty of Rehabilitation Sciences, Nishikyushu University, Saga.
Int J Rehabil Res. 2020 Sep;43(3):228-234. doi: 10.1097/MRR.0000000000000413.
A short period of adaptation to a prismatic shift of the visual field to the right briefly but significantly improves left unilateral spatial neglect. Additionally, prism adaptation affects multiple modalities, including processes of vision, auditory spatial attention, and sound localization. This non-randomized, single-center, controlled trial aimed to examine the immediate effects of prism adaptation on the sound-localization abilities of patients with left unilateral spatial neglect using a simple source localization test. Subjects were divided by self-allocation into a prism-adaptation group (n = 11) and a control group (n = 12). At baseline, patients with left unilateral spatial neglect showed a rightward deviation tendency in the left space. This tendency to right-sided bias in the left space was attenuated after prism adaptation. However, no changes were observed in the right space of patients with left unilateral spatial neglect after prism adaptation, or in the control group. Our results suggest that prism adaptation improves not only vision and proprioception but also auditory attention in the left space of patients with left unilateral spatial neglect. Our findings demonstrate that a single session of prism adaptation can significantly improve sound localization in patients with left unilateral spatial neglect. However, in this study, it was not possible to accurately determine whether the mechanism was a chronic change in head orientation or a readjustment of the spatial representation of the brain; thus, further studies need to be considered.
短时间适应视野向右的棱镜偏移可短暂但显著改善左侧单侧空间忽视。此外，棱镜适应会影响多种感觉模态，包括视觉、听觉空间注意力和声音定位过程。这项非随机、单中心对照试验旨在使用简单的声源定位测试来检验棱镜适应对左侧单侧空间忽视患者声音定位能力的即时影响。受试者通过自我分配分为棱镜适应组（n = 11）和对照组（n = 12）。在基线时，左侧单侧空间忽视患者在左侧空间表现出向右偏斜的趋势。棱镜适应后，左侧空间向右侧偏倚的这种趋势减弱。然而，左侧单侧空间忽视患者在棱镜适应后其右侧空间以及对照组均未观察到变化。我们的结果表明，棱镜适应不仅能改善左侧单侧空间忽视患者的视觉和本体感觉，还能改善其左侧空间的听觉注意力。我们的研究结果表明，单次棱镜适应可显著改善左侧单侧空间忽视患者的声音定位。然而，在本研究中，无法准确确定其机制是头部方向的慢性改变还是大脑空间表征的重新调整；因此，需要考虑进一步的研究。
