Department of Ophthalmology, Beijing Chaoyang Hospital, affiliated with Capital Medical University, Beijing, China.
J Int Med Res. 2020 Aug;48(8):300060520929865. doi: 10.1177/0300060520929865.
This report describes the presence of endophthalmitis after phacoemulsification in a 66-year-old woman. The patient presented with ocular redness and pain, as well as hypopyon in the anterior chamber and reduction of visual acuity to hand motion. Intraocular fluid examination revealed a lipopolysaccharide level of >2.5, which suggested bacterial endophthalmitis. The patient was promptly treated with intravitreal ceftazidime 2 mg and vancomycin 1 mg, as well as intravenous infusion of cefuroxime 750 mg, all administered simultaneously at 12-hour intervals. She also received topical levofloxacin eyedrops, once per hour. Subsequently, pathology culture confirmed the presence of the Gram-negative bacillus, . The presence of lipopolysaccharide in intraocular fluid is an important early indicator of bacterial endophthalmitis, which can provide guidance for clinical treatment.
本报告描述了一例 66 岁女性在超声乳化术后发生眼内炎的情况。患者出现眼部红肿和疼痛，前房出现积脓，视力下降至手动。眼内液检查发现脂多糖水平>2.5，提示细菌性眼内炎。患者立即接受玻璃体腔注射头孢他啶 2mg 和万古霉素 1mg，以及静脉输注头孢呋辛 750mg，均 12 小时一次，同时给予左氧氟沙星滴眼液滴眼，每小时一次。随后，病理培养证实存在革兰氏阴性杆菌。眼内液中脂多糖的存在是细菌性眼内炎的重要早期指标，可以为临床治疗提供指导。
