Olalla Julián, Correa Ana M, Martín-Escalante M Dolores, Hortas M Luisa, Martín-Sendarrubias María Jesús, Fuentes Víctor, Sena Gabriel, García-Alegría Javier
Internal Medicine Unit, Marbella, SPAIN.
Microbiology Unit, Marbella, SPAIN.
QJM. 2020 Aug 10. doi: 10.1093/qjmed/hcaa238.
Asymptomatic carriers of SARS-CoV-2 can be a vehicle for transmission of the infection. This fact is of particular importance in the case of healthcare workers (HCWs).
Cross-sectional study in HCWs in a medium size hospital in the South of Spain.
between April 15 and 25, 2020, naso and oropharyngeal PCR determination was performed together with IgG and IgM antibody determination by immunochromatography to the HCWs of the Costa del Sol Hospital in Marbella of the units involved in patient care with CoVID-19: Emergencies, Intensive Care and Anesthesia, Internal Medicine and Pneumology. Other units not directly involved in the care of these patients were offered to participate. On the day of sampling, a health questionnaire was answered, reporting symptoms on the same day and in the previous fourteen days.
498 HCWs were studied. Two individuals were detected with PCR for SARS-CoV-2 positive. Both were asymptomatic on the day of sampling, but one of them had had a CoVID-19 compatible picture in the previous two weeks and had positive IgG and IgM; therefore, only one subject was truly asymptomatic carrier (0.2%). 9 workers with positive IgG (1.8%) were detected.
the prevalence of asymptomatic carriers among health workers of the services directly involved in the care of patients with CoVID-19 was very low in our center. This type of strategy can be one more tool in controlling the pandemic.
严重急性呼吸综合征冠状病毒2(SARS-CoV-2)的无症状携带者可能是感染传播的媒介。这一事实在医护人员(HCWs)中尤为重要。
在西班牙南部一家中型医院对医护人员进行的横断面研究。
2020年4月15日至25日,对马尔韦利亚太阳海岸医院参与新冠肺炎患者护理的科室(急诊科、重症监护室、麻醉科、内科和肺病科)的医护人员进行鼻和口咽聚合酶链反应(PCR)检测,并通过免疫层析法检测IgG和IgM抗体。其他未直接参与这些患者护理的科室也被邀请参与。在采样当天,医护人员填写了一份健康问卷,报告当天及前十四天的症状。
共研究了498名医护人员。两名个体的SARS-CoV-2 PCR检测呈阳性。两人在采样当天均无症状,但其中一人在过去两周内有与新冠肺炎相符的症状表现,且IgG和IgM呈阳性;因此,只有一名受试者是真正的无症状携带者(0.2%)。检测到9名IgG呈阳性的工作人员(1.8%)。
在我们中心,直接参与新冠肺炎患者护理的服务部门的医护人员中无症状携带者的患病率非常低。这种策略可以成为控制疫情的又一工具。