Artemisinin Research Center, and Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China.
Artemisinin Research Center, and Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China.
Pharmacol Ther. 2020 Dec;216:107658. doi: 10.1016/j.pharmthera.2020.107658. Epub 2020 Aug 8.
As the first-line antimalarial drugs, artemisinins gained wide acceptance after the emergence of resistance to chloroquine in the 1950s. Artemisinin-based drugs have saved lives, especially in developing countries. The discovery of artemisinin was unique, timely, and fascinating, and the benefits of artemisinin were with far-reaching implications. Herein, we will give a brief description of various aspects of the development of artemisinin and discuss the position and perspectives of artemisinin-based drugs.
作为一线抗疟药物，青蒿素在 20 世纪 50 年代氯喹耐药性出现后得到广泛认可。青蒿素类药物挽救了生命，尤其是在发展中国家。青蒿素的发现是独特的、及时的、引人入胜的，青蒿素的益处具有深远的意义。在此，我们将简要描述青蒿素发展的各个方面，并讨论青蒿素类药物的地位和观点。
