匈牙利灰牛中与估计育种值和牛角颜色相关的标记物鉴定
Identification of markers associated with estimated breeding value and horn colour in Hungarian Grey cattle.
作者信息
Zsolnai Attila, Kovács András, Kaltenecker Endre, Anton István
机构信息
NAIK-Research Institute for Animal Breeding, Nutrition and Meat Science, Gesztenyés u. 1., 2053 Herceghalom, Hungary.
Association of Hungarian Grey Cattle Breeders, Lőportár u. 16.,1134 Budapest, Hungary.
出版信息
Anim Biosci. 2021 Apr;34(4):482-488. doi: 10.5713/ajas.19.0881. Epub 2020 May 12.
OBJECTIVE
This study was conducted to estimate effect of single nucleotide polymorphisms (SNP) on the estimated breeding value of Hungarian Grey (HG) bulls and to find markers associated with horn colour.
METHODS
Genotypes 136 HG animals were determined on Geneseek high-density Bovine SNP 150K BeadChip. A multi-locus mixed-model was applied for statistical analyses.
RESULTS
Six SNPs were identified to be associated (-log10P>10) with green and white horn. These loci are located on chromosome 1, 3, 9, 18, and 25. Seven loci (on chromosome 1, 3, 6, 9, 10, 28) showed considerable association (-log10P>10) with the estimated breeding value.
CONCLUSION
Analysis provides markers for further research of horn colour and supplies markers to achieve more effective selection work regarding estimated breeding value of HG.
目的
本研究旨在评估单核苷酸多态性（SNP）对匈牙利灰牛（HG）公牛估计育种值的影响，并寻找与牛角颜色相关的标记。
方法
使用Geneseek高密度牛SNP 150K芯片对136头HG动物进行基因分型。采用多位点混合模型进行统计分析。
结果
鉴定出6个与绿色和白色牛角相关的SNP（-log10P>10）。这些位点位于1、3、9、18和25号染色体上。7个位点（位于1、3、6、9、10、28号染色体上）与估计育种值显示出显著关联（-log10P>10）。
结论
该分析为牛角颜色的进一步研究提供了标记，并为HG估计育种值的更有效选择工作提供了标记。
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