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沙门氏菌致突变性试验:IV. 300种化学物质的测试结果。

Salmonella mutagenicity tests: IV. Results from the testing of 300 chemicals.

作者信息

Zeiger E, Anderson B, Haworth S, Lawlor T, Mortelmans K

机构信息

Cellular and Genetic Toxicology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina.

出版信息

Environ Mol Mutagen. 1988;11 Suppl 12:1-157.

PMID:3277844
Abstract

Three hundred chemicals were tested for mutagenicity, under code, in Salmonella typhimurium, using a preincubation protocol. All tests were performed in the absence of exogenous metabolic activation, and in the presence of liver S-9 from Aroclor-induced male Sprague-Dawley rats and Syrian hamsters. The results and data from these tests are presented.

摘要

采用预孵育方案,对三百种化学物质进行了编码下的鼠伤寒沙门氏菌致突变性测试。所有测试均在无外源性代谢活化的情况下进行,并在存在来自经艾氏剂诱导的雄性斯普拉格-道利大鼠和叙利亚仓鼠的肝脏S-9的情况下进行。展示了这些测试的结果和数据。

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