Mortelmans K, Haworth S, Lawlor T, Speck W, Tainer B, Zeiger E
Environ Mutagen. 1986;8 Suppl 7:1-119.
This publication includes data of Salmonella mutagenicity results on 270 coded chemicals, encompassing 329 tests performed by three laboratories under contract to the National Toxicology Program (NTP). The preincubation modification of the Salmonella/mammalian microsome assay was used to test chemicals in up to five Salmonella strains in the presence and absence of rat and hamster liver S-9. With a few exceptions, inter- and intralaboratory reproducibility was good.
本出版物包含270种编码化学品的沙门氏菌致突变性结果数据,涵盖了由与国家毒理学计划(NTP)签订合同的三个实验室进行的329项测试。沙门氏菌/哺乳动物微粒体试验的预孵育改良法用于在有和没有大鼠及仓鼠肝脏S-9的情况下,对多达五种沙门氏菌菌株中的化学品进行测试。除了少数例外情况,实验室间和实验室内的重现性都很好。