Hata K, Hata T, Kitao M
Department of Obstetrics and Gynecology, Shimane Medical University, Izumo, Japan.
Gynecol Obstet Invest. 1988;25(1):16-22. doi: 10.1159/000293739.
The size of the fetal adrenal gland was determined using ultrasonography in 346 fetuses with no complications at 28-40 weeks of gestation and in 12 fetuses of abnormal pregnancies (8 intrauterine growth retardations, 2 anencephalies, 1 intrauterine fetal death and 1 fetus of a mother who had been on steroids for treatment of systemic lupus erythematosus). The fetal adrenal gland area (FAGA), circumference (FAGC) and length (FAGL) were calculated. In 12 abnormal fetuses, FAGA values always fell below the mean +/- 2 SD. Deviations from the normal values were seen in 9 out of 12 cases (75%) in FAGC and in 4 out of 12 cases (33.3%) in FAGL. Of these pregnancies, 4 (33.3%) resulted in intrauterine fetal or neonatal death, and 2 neonates (16.6%) had to be admitted to the neonatal intensive care unit. Measurement of the fetal adrenal gland, especially of the FAGA, should be a pertinent diagnostic tool for perinatologists to manage and control high-risk pregnancies.
在346例妊娠28至40周无并发症的胎儿以及12例异常妊娠胎儿（8例胎儿宫内生长受限、2例无脑儿、1例宫内胎儿死亡、1例母亲因系统性红斑狼疮接受类固醇治疗的胎儿）中，采用超声检查测定胎儿肾上腺大小。计算胎儿肾上腺面积（FAGA）、周长（FAGC）和长度（FAGL）。在12例异常胎儿中，FAGA值始终低于均值±2标准差。12例中有9例（75%）FAGC以及4例（33.3%）FAGL出现与正常值的偏差。这些妊娠中，4例（33.3%）导致宫内胎儿或新生儿死亡，2例新生儿（16.6%）需入住新生儿重症监护病房。测量胎儿肾上腺，尤其是FAGA，应为围产医学专家管理和控制高危妊娠的相关诊断工具。
