Hata T, Aoki S, Hata K, Takamiya O, Kitao M
Department of Obstetrics and Gynecology, Shimane Medical University, Izumo, Japan.
Gynecol Obstet Invest. 1987;24(2):80-5. doi: 10.1159/000298783.
Forty-eight ultrasonographic examinations done to assess growth of the fetal adrenal gland and placental aging were performed on 17 normal fetuses and 7 fetuses with intrauterine growth retardation (IUGR). Gestational age ranged from 30 to 40 weeks. High correlations of the area of fetal adrenal gland (FAGA) with gestational age were noted in the normal fetuses (r = 0.96, p less than 0.001) and IUGR (r = 0.93, p less than 0.001), respectively. FAGA correlated well with the level of estrogens in the maternal urine (r = 0.65, p less than 0.001). When the value of FAGA was 300 mm2 and over, the level of estrogens in the maternal urine was 20 mg/day and over, and all were normal fetuses. In cases of grade I and II placentas, the mean values of FAGA in normal fetuses were larger than those in IUGR, respectively (p less than 0.001). In the case of IUGR with placental infarction and hematoma associated with severe toxemia of pregnancy, the FAGA was significantly small.
对17例正常胎儿和7例宫内生长受限（IUGR）胎儿进行了48次超声检查，以评估胎儿肾上腺的生长和胎盘老化情况。孕周为30至40周。正常胎儿（r = 0.96，p < 0.001）和IUGR胎儿（r = 0.93，p < 0.001）的胎儿肾上腺面积（FAGA）与孕周均呈高度相关。FAGA与母体尿中雌激素水平相关性良好（r = 0.65，p < 0.001）。当FAGA值≥300 mm²时，母体尿中雌激素水平≥20 mg/天，且均为正常胎儿。在Ⅰ级和Ⅱ级胎盘的情况下，正常胎儿的FAGA平均值分别大于IUGR胎儿（p < 0.001）。在伴有胎盘梗死和血肿且与重度妊娠中毒相关的IUGR病例中，FAGA明显较小。
