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肾移植患者出现典型症状且非典型症状已缓解的新型冠状病毒肺炎

COVID-19 in Renal Transplant Patient Presenting With Active Typical Symptoms and Resolved Atypical Symptoms.

作者信息

Adapa Sreedhar, Konala Venu Madhav, Naramala Srikanth, Daggubati Subba Rao, Koduri Narayana Murty, Gayam Vijay, Chenna Avantika

机构信息

Adventist Medical Center, Hanford, CA, USA.

Ashland Bellefonte Cancer Center, Ashland, KY, USA.

出版信息

J Investig Med High Impact Case Rep. 2020 Jan-Dec;8:2324709620949307. doi: 10.1177/2324709620949307.

Abstract

The novel coronavirus disease has brought the world to standstill with high infectivity and rapid transmission. The disease caused by novel coronavirus is termed as coronavirus disease 2019 (COVID-19). We present the case of a renal transplant patient who was infected with COVID-19 through community spread and presented with fever and gastrointestinal symptoms. Transplant recipients are particularly vulnerable because of the immunosuppressed state. These patients can shed a virus for a prolonged period and can have a higher load of the virus. There have been no COVID-19 cases transmitted through organ donation. Preinfection immunological impairment can aggravate the severity of the infection. The transplant team plays a crucial role in donor and recipient evaluation and guiding the timing of the transplant. Although specific published data are lacking with regard to transplant recipients, they should follow the same precautions as the general population, like avoiding nonessential travel and practice social distancing.

摘要

新型冠状病毒病以高传染性和快速传播使世界陷入停滞。由新型冠状病毒引起的疾病被称为2019冠状病毒病(COVID-19)。我们报告一例肾移植患者,该患者通过社区传播感染了COVID-19,并出现发热和胃肠道症状。由于处于免疫抑制状态,移植受者特别脆弱。这些患者可能长时间排出病毒,且病毒载量可能更高。目前尚无通过器官捐赠传播COVID-19病例的情况。感染前的免疫损伤会加重感染的严重程度。移植团队在供体和受体评估以及指导移植时机方面起着关键作用。尽管缺乏关于移植受者的具体公开数据,但他们应采取与普通人群相同的预防措施,如避免不必要的旅行并保持社交距离。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e22/7425242/495128bc8a80/10.1177_2324709620949307-fig1.jpg

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