Georgia Pain Care, Stockbridge, GA 30281, USA.
KC Pain Centers, Lee's Summit, MO 64086, USA.
Pain Manag. 2020 Sep;10(5):291-300. doi: 10.2217/pmt-2020-0033. Epub 2020 Aug 11.
Previous studies of 10 kHz spinal cord stimulation demonstrated its safety and efficacy for treatment of neuropathic pain of the trunk and/or limbs. This study analyzed data from a subset of subjects with painful diabetic neuropathy enrolled in a prospective, multicenter study of peripheral polyneuropathy with various etiologies. Of the eight subjects that had permanent devices, seven attended the 12-month follow-up assessment. At 12 months, 6/7 subjects were treatment responders (≥50% pain relief) and had pain remission (visual analog scale ≤ 3.0 cm). Worsening of neurologic deficits was not reported in any subject. Instead, 5/7 subjects showed improvements in sensory testing and/or reflexes. These results support further investigation of 10 kHz spinal cord stimulation as a safe and effective treatment for intractable painful diabetic neuropathy.
先前对 10kHz 脊髓刺激的研究证明了其治疗躯干和/或肢体神经病理性疼痛的安全性和有效性。本研究分析了在一项针对各种病因的周围多发性神经病的前瞻性、多中心研究中，入组的伴有痛性糖尿病性神经病的亚组受试者的数据。在 8 名有永久性装置的受试者中，有 7 名参加了 12 个月的随访评估。在 12 个月时，6/7 名受试者为治疗应答者（疼痛缓解≥50%），并且疼痛缓解（视觉模拟评分≤3.0cm）。在任何受试者中均未报告神经功能缺损恶化的情况。相反，5/7 名受试者的感觉测试和/或反射得到改善。这些结果支持进一步研究 10kHz 脊髓刺激作为治疗难治性痛性糖尿病性神经病的安全有效的方法。
