Cheng Y S
Am J Obstet Gynecol. 1977 Aug 1;128(7):812-22. doi: 10.1016/0002-9378(77)90727-x.
Clinical features of pregnancy in women with liver cirrhosis and/or portal hypertension have been reviewed. Termination of pregnancy is seldom indicated in a woman with compensated cirrhosis or a young woman with extrahepatic venous obstruction. However, the risk of spontaneous abortion is increased in cirrhotic women without shunt even if there is no deterioration of liver function. The risk of bleeding from esophageal varices or deterioration of liver function is usually unpredictable. Shunt surgery can be done with relatively little effect on both the mother and the fetus if conservative measurements fail to control the hematemesis. Vaginal delivery can be anticipated in most women, and cesarean section should be preserved for obstetric indications. The risk of postpartum hemorrhage is greatly increased, particularly in patients with previous shunt surgery. Perinatal loss is high because of the increased rate of premature delivery and stillbirth. Maternal prognosis is grave in women with cirrhosis.
已对肝硬化和/或门静脉高压症女性的妊娠临床特征进行了综述。对于代偿期肝硬化女性或患有肝外静脉阻塞的年轻女性，很少需要终止妊娠。然而，即使肝功能没有恶化，无分流的肝硬化女性自然流产的风险也会增加。食管静脉曲张出血或肝功能恶化的风险通常无法预测。如果保守措施无法控制呕血，分流手术对母亲和胎儿的影响相对较小。大多数女性可以预期经阴道分娩，剖宫产应仅用于产科指征。产后出血的风险会大大增加，尤其是既往接受过分流手术的患者。由于早产和死产率增加，围产期损失较高。肝硬化女性的母亲预后严重。
