药物治疗阿片类药物使用障碍对监禁人群丙型肝炎发病率的影响：系统评价。
The Impact of Medications for Opioid Use Disorder on Hepatitis C Incidence Among Incarcerated Persons: A Systematic Review.
机构信息
Department of Internal Medicine, Section of Infectious Diseases, Yale School of Medicine, New Haven, CT, USA.
Department of Medicine, Division of Geographic Medicine and Infectious Diseases, Tufts University School of Medicine, 136 Harrison Avenue, Boston, MA 02111, USA.
出版信息
Infect Dis Clin North Am. 2020 Sep;34(3):559-584. doi: 10.1016/j.idc.2020.06.011.
Abstract
Hepatitis C virus (HCV) is highly prevalent in the criminal justice system and in persons who inject drugs, particularly opioids. Data on the impact of medications for opioid use disorder (MOUD) are abundant for infectious and noninfectious outcomes but are limited for justice-involved settings. This systematic review and meta-analysis focuses on the impact of MOUD on HCV incidence for persons in prisons and jails. Six studies were included in the qualitative synthesis, of which four were included for meta-analysis. A varied MOUD effect on HCV incidence was observed in part due to wide variability in prison and jail risk environments.
摘要
丙型肝炎病毒（HCV）在刑事司法系统和注射毒品者中（尤其是阿片类药物）高度流行。关于治疗阿片类药物使用障碍（MOUD）药物对传染病和非传染病结果影响的数据很多，但在涉及司法的环境中数据有限。本系统评价和荟萃分析主要关注 MOUD 对监狱和看守所内人员 HCV 发病率的影响。定性综合分析纳入了 6 项研究，其中 4 项纳入荟萃分析。由于监狱和看守所风险环境的巨大差异，MOUD 对 HCV 发病率的影响也各不相同。
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