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在两项细菌短期试验中精制烟用香料(RSF)无遗传毒性活性。

Absence of genotoxic activity of refined smoke flavor (RSF) in two bacterial short-term tests.

作者信息

Jenek J, Quillardet P, Chomiak D, Borys A, Hofnung M

机构信息

Unité de Programmation Moléculaire et Toxicologie Génétique, CNRS LA271, Institut Pasteur, Paris, France.

出版信息

Mutat Res. 1988 Feb;204(2):235-8. doi: 10.1016/0165-1218(88)90094-8.

DOI:10.1016/0165-1218(88)90094-8
PMID:3278215
Abstract

The genotoxic activities of refined smoke flavor (RSF) produced in Poland and used in food processing were investigated in 2 bacterial short-term tests. Its mutagenic activity was examined in the Salmonella/histidine plate assay and its SOS-inducing capacity in the SOS Chromotest both without and with 'activation' by a rat liver homogenate. No genotoxic activity was detected using these 2 bacterial tests.

摘要

对在波兰生产并用于食品加工的精制烟用香料(RSF)的遗传毒性活性进行了两项细菌短期试验研究。在沙门氏菌/组氨酸平板试验中检测其诱变活性,并在SOS显色试验中检测其在有无大鼠肝脏匀浆“活化”情况下的SOS诱导能力。使用这两项细菌试验均未检测到遗传毒性活性。

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