Jenek J, Quillardet P, Chomiak D, Borys A, Hofnung M
Unité de Programmation Moléculaire et Toxicologie Génétique, CNRS LA271, Institut Pasteur, Paris, France.
Mutat Res. 1988 Feb;204(2):235-8. doi: 10.1016/0165-1218(88)90094-8.
The genotoxic activities of refined smoke flavor (RSF) produced in Poland and used in food processing were investigated in 2 bacterial short-term tests. Its mutagenic activity was examined in the Salmonella/histidine plate assay and its SOS-inducing capacity in the SOS Chromotest both without and with 'activation' by a rat liver homogenate. No genotoxic activity was detected using these 2 bacterial tests.
对在波兰生产并用于食品加工的精制烟用香料(RSF)的遗传毒性活性进行了两项细菌短期试验研究。在沙门氏菌/组氨酸平板试验中检测其诱变活性,并在SOS显色试验中检测其在有无大鼠肝脏匀浆“活化”情况下的SOS诱导能力。使用这两项细菌试验均未检测到遗传毒性活性。