Cole M S, Minifee P K, Wolma F J
Department of Surgery, University of Texas Medical Branch, Galveston 77550.
Surgery. 1988 Mar;103(3):271-7.
Skin and soft tissue necrosis is a rare complication of anticoagulation therapy. Two patients who exhibited the spectrum of this disorder are described. The clinical features, etiology, pathophysiology, and treatment of coumarin skin necrosis are outlined, and the English-language literature is reviewed.
