Department of Otolaryngology, Japanese Red Cross Society Himeji Hospital, Himeji, Japan.
Department of Otolaryngology Head and Neck Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan.
J Int Adv Otol. 2020 Aug;16(2):291-294. doi: 10.5152/iao.2020.6779.
Although basal cell carcinoma (BCC) often occurs in the head and neck region, BCC in the middle ear is extremely rare. As far as we could determine, only five cases of BCC in the middle ear have been reported previously in the literature. We present the case of a 54-year-old Japanese man with BCC in the middle ear. Preoperative histopathologic examination indicated the possibility of skin appendage tumor. Mastoidectomy and extirpation of the lesion were performed, and the resected tumor was finally diagnosed as BCC. Four months after the initial surgery, the patient had local recurrence and reoperation, and postoperative radiotherapy was given. The patient had repeat local recurrence in the parapharyngeal space 3 years and 2 months following postoperative radiotherapy. The patient did not respond to two courses of chemotherapy with cisplatin and 5-fluorouracil, and eventually died of the primary disease 4 years and 7 months after the initial surgical treatment. We reviewed the five cases previously reported in the literature concerning BCC in the middle ear. More case reports concerning BCC in the middle ear are needed to determine its appropriate management.
虽然基底细胞癌（BCC）通常发生在头部和颈部区域，但中耳 BCC 极为罕见。据我们所知，之前文献中仅报道过 5 例中耳 BCC。我们报告了 1 例 54 岁日本男性中耳 BCC 病例。术前组织病理学检查提示皮肤附属器肿瘤的可能性。行乳突切除术和病变切除术，切除的肿瘤最终诊断为 BCC。初次手术后 4 个月，患者出现局部复发并再次手术，术后给予放疗。放疗后 3 年 2 个月，患者在咽旁间隙再次出现局部复发。患者对顺铂和 5-氟尿嘧啶的两个疗程化疗无反应，最终在初次手术治疗后 4 年 7 个月死于原发性疾病。我们复习了之前文献中报道的 5 例中耳 BCC 病例。需要更多关于中耳 BCC 的病例报告来确定其合适的治疗方法。
