Kawana M, Nonomura N, Okura T, Nakano Y, Ikarashi F
Department of Otolaryngology, Niigata University, School of Medicine, Japan.
Nihon Jibiinkoka Gakkai Kaiho. 1996 May;99(5):645-52. doi: 10.3950/jibiinkoka.99.645.
Between 1982 and 1994, 21 patients with malignant tumors of the external auditory canal and middle ear were treated at the Department of Otolaryngology, Niigata University. Eleven patients with tumors of the external auditory canal and 10 tumors of the middle ear were registered. There were 9 males and 12 females, and their ages ranged from 10 to 80 years (median: 61). Otalgia, otorrhea or bloody otorrhea were the chief complaints of most patients with external auditory canal of middle ear tumors. Pathological examination revealed squamous cell carcinoma in 16 patients, adenoid cystic carcinoma in 3 patients, and basal cell carcinoma and rhabdomyosarcoma in 1 patient each. External auditory canal tumors were surgically excised, while radical mastoidectomy and subsequent irradiation were performed for the middle ear tumors. The five-year survival rate determined by the Kaplan-Meier method, was 77.8% for patients with external auditory canal tumors and 40% for those with middle ear tumors.
1982年至1994年间,新潟大学耳鼻喉科收治了21例外耳道及中耳恶性肿瘤患者。登记在册的有11例外耳道肿瘤患者和10例中耳肿瘤患者。其中男性9例,女性12例,年龄范围为10至80岁(中位数:61岁)。耳痛、耳漏或血性耳漏是大多数外耳道及中耳肿瘤患者的主要症状。病理检查显示,16例为鳞状细胞癌,3例为腺样囊性癌,1例为基底细胞癌,1例为横纹肌肉瘤。外耳道肿瘤采用手术切除,中耳肿瘤则行根治性乳突切除术并随后进行放疗。采用Kaplan-Meier法确定的五年生存率,外耳道肿瘤患者为77.8%,中耳肿瘤患者为40%。