Bolaji Paul, Kukoyi Babatunde, Ahmad Nasar, Wharton Chris
Stroke Medicine, New Cross Hospital, Wolverhampton, UK
Stroke Medicine, New Cross Hospital, Wolverhampton, UK.
BMJ Case Rep. 2020 Aug 11;13(8):e236820. doi: 10.1136/bcr-2020-236820.
A 63-year-old man was admitted with left-sided weakness and subsequent focal seizures following a recent diagnosis of Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pneumonia in a nearby hospital. He developed status epilepticus and became comatose, requiring intensive care unit admission for invasive ventilation. Imaging done at admission confirmed extensive cerebral venous sinus thrombosis (CVST) with bilateral venous cortical infarcts and acute cortical haemorrhage. No known risk factor for CVST could be identified. He improved with anticoagulation and antiepileptic therapy. He was subsequently transferred to an inpatient rehabilitation facility. Although Coronavirus disease 19 (COVID-19) infection has been previously associated with thrombotic complications, these mostly relate to the pulmonary vasculature. We present this case as a potential association between CVST and COVID-19 infection.
一名63岁男性因近期在附近医院被诊断为严重急性呼吸综合征冠状病毒2（SARS-CoV-2）肺炎后出现左侧肢体无力及随后的局灶性癫痫发作而入院。他发展为癫痫持续状态并昏迷，需要入住重症监护病房进行有创通气。入院时的影像学检查证实广泛的脑静脉窦血栓形成（CVST），伴有双侧静脉性皮质梗死和急性皮质出血。未发现已知的CVST危险因素。他通过抗凝和抗癫痫治疗后病情好转。随后他被转至住院康复机构。虽然冠状病毒病19（COVID-19）感染此前已与血栓形成并发症相关，但这些大多与肺血管系统有关。我们报告此病例，提示CVST与COVID-19感染之间可能存在关联。
