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医生配备直升机与地面紧急医疗服务对儿科创伤患者死亡率的影响:一项回顾性全国队列研究。

Association between physician-staffed helicopter versus ground emergency medical services and mortality for pediatric trauma patients: A retrospective nationwide cohort study.

机构信息

Department of Emergency and Critical Care Medicine, Faculty of Medicine, University of Tsukuba, Ibaraki, Japan.

Department of Emergency and Critical Care Medicine, National Hospital Organization Mito Medical Center, Ibaraki, Japan.

出版信息

PLoS One. 2020 Aug 12;15(8):e0237192. doi: 10.1371/journal.pone.0237192. eCollection 2020.

Abstract

BACKGROUND

Helicopter emergency medical services' (HEMS) effectiveness for pediatric trauma patients remains unclear. We aimed to examine the relation between HEMS and reduced mortality in pediatric trauma patients.

METHODS

This retrospective cohort study utilized data from the Japan Trauma Data Bank, a national multicenter clinical trauma database. Participants were aged <18 years, admitted between 2004 and 2015, and transported from the scene to the hospital by HEMS or ground emergency medical services (GEMS). We used a standardized mortality ratio (SMR) weight method, and fitted a marginal structural model to adjust for measured confounders. The SMR weight was calculated using the estimation of the propensity scores. A logistic regression model was used with the baseline independent variables to estimate the propensity score.

RESULTS

Overall, 5,947 patients were identified in our study: 453 were transported by HEMS and 5,494 by GEMS. The mean injury severity score in the HEMS group was significantly higher than that in the GEMS group17.0 (Standard deviation = 11.0) vs 12.2 (Standard deviation = 9.2), p < .001. In-hospital mortality was higher in the HEMS group than that in the GEMS group in the unadjusted analysis (3.8% vs 1.3%, respectively; p < .001). After adjusting for covariates, HEMS transport was not associated with reduced hospital mortality. (odds ratio = 0.82, 95% confidence interval = 0.42-1.58).

CONCLUSIONS

HEMS was not associated with reduced mortality among pediatric trauma patients compared with GEMS in this nationwide study. Further investigation is necessary to determine who clearly benefits from HEMS as compared to GEMS.

摘要

背景

直升机紧急医疗服务(HEMS)对儿科创伤患者的效果仍不清楚。我们旨在研究 HEMS 与儿科创伤患者死亡率降低之间的关系。

方法

本回顾性队列研究使用了日本创伤数据库(一个国家多中心临床创伤数据库)的数据。参与者年龄<18 岁,于 2004 年至 2015 年期间入院,由 HEMS 或地面紧急医疗服务(GEMS)从现场运往医院。我们使用标准化死亡率比(SMR)权重方法,并拟合边缘结构模型以调整测量混杂因素。SMR 权重是通过估计倾向得分来计算的。使用逻辑回归模型和基线独立变量来估计倾向得分。

结果

在我们的研究中,共有 5947 名患者被确定:453 名由 HEMS 运送,5494 名由 GEMS 运送。HEMS 组的平均损伤严重程度评分明显高于 GEMS 组(17.0 [标准差=11.0] 与 12.2 [标准差=9.2],p<0.001)。未调整分析中,HEMS 组的院内死亡率高于 GEMS 组(分别为 3.8%和 1.3%,p<0.001)。在调整协变量后,HEMS 转运与降低医院死亡率无关(比值比=0.82,95%置信区间=0.42-1.58)。

结论

在这项全国性研究中,与 GEMS 相比,HEMS 并未降低儿科创伤患者的死亡率。需要进一步研究以确定与 GEMS 相比,谁明显受益于 HEMS。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9356/7423096/8f86e0cc12d2/pone.0237192.g001.jpg

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