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养老院痴呆患者的姑息治疗:服务评估和死亡率的风险因素。

Palliative care for nursing home patients with dementia: service evaluation and risk factors of mortality.

机构信息

Department of General Psychiatry, Songde Branch (Taipei City Psychiatric Center), Taipei City Hospital, 309 Sung-Te Road, Taipei, 110, Taiwan.

Department of Psychiatry, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan.

出版信息

BMC Palliat Care. 2020 Aug 12;19(1):122. doi: 10.1186/s12904-020-00627-9.

Abstract

BACKGROUND

Difficulties in prognostication are common deterrents to palliative care among dementia patients. This study aimed to evaluate the effectiveness of palliative care in reducing the extent of utilization of medical services and the potential risk factors of mortality among dementia patients receiving palliative care.

METHODS

We surveyed dementia patients involved in a palliative care program at a long-term care facility in Taipei, Taiwan. We enrolled 57 patients with advanced dementia (clinical dementia rating ≥ 5 or functional assessment staging test stage 7b). We then compared the extent of their utilization of medical services before and after the provision of palliative care. Based on multivariable logistic regression, we identified potential risk factors before and after the provision of palliative care associated with 6-month mortality.

RESULTS

The utilization of medical services was significantly lower among dementia patients after the provision of palliative care than before, including visits to medical departments (p < 0.001), medications prescribed (p < 0.001), frequency of hospitalization (p < 0.001), and visits to the emergency room (p < 0.001). Moreover, patients dying within 6 months after the palliative care program had a slightly but not significantly higher number of admissions before receiving hospice care (p = 0.058) on univariate analysis. However, no significant differences were observed in multivariate analysis.

CONCLUSIONS

The provision of palliative care to dementia patients reduces the extent of utilization of medical services. However, further studies with larger patient cohorts are required to stratify the potential risk factors of mortality in this patient group.

摘要

背景

在痴呆症患者中,预后困难是进行姑息治疗的常见障碍。本研究旨在评估姑息治疗在减少接受姑息治疗的痴呆症患者医疗服务利用程度和死亡潜在风险因素方面的效果。

方法

我们调查了台湾台北一家长期护理机构姑息治疗计划中的痴呆症患者。我们纳入了 57 名患有晚期痴呆症(临床痴呆评定量表≥5 或功能评估分期测试阶段 7b)的患者。然后,我们比较了在提供姑息治疗前后他们医疗服务的利用程度。基于多变量逻辑回归,我们确定了在提供姑息治疗前后与 6 个月死亡率相关的潜在风险因素。

结果

与提供姑息治疗前相比,痴呆症患者接受姑息治疗后医疗服务的利用程度显著降低,包括就诊于医疗部门(p<0.001)、开处方的药物(p<0.001)、住院频率(p<0.001)和急诊就诊(p<0.001)。此外,在姑息治疗计划后 6 个月内死亡的患者在接受临终关怀前的入院次数略高(p=0.058),但单因素分析无统计学差异。然而,多因素分析未观察到显著差异。

结论

为痴呆症患者提供姑息治疗可降低医疗服务的利用程度。然而,需要进一步研究以分层该患者群体的死亡潜在风险因素。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1903/7425598/08e29d46c0cd/12904_2020_627_Fig1_HTML.jpg

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