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表现为Wellens综合征的非动脉粥样硬化性心肌梗死

Non-Atherosclerotic Myocardial Infarction With a Presentation of Wellens Syndrome.

作者信息

Jamshaid Muhammad B, Shahzad Aamir, Iqbal Phool, Yousaf Zohaib

机构信息

Internal Medicine, Hamad General Hospital, Doha, QAT.

Medicine, Hamad General Hospital, Doha, QAT.

出版信息

Cureus. 2020 Jul 10;12(7):e9116. doi: 10.7759/cureus.9116.

DOI:10.7759/cureus.9116
PMID:32789059
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7417120/
Abstract

Myocardial infarction (MI) is a critical event that needs timely diagnosis and prompt management. Wellens syndrome can progress to MI if not managed in a timely manner. It implies the underlying critical stenosis of the left anterior descending (LAD) artery of the heart. In this report, we discuss an interesting presentation of pseudo-Wellens syndrome in a hypertensive middle-aged woman admitted as a case of Non-ST-elevation myocardial infarction (NSTEMI). During the hospital stay, she had an episode of chest pain with typical ECG changes, suggesting Wellens syndrome. However, upon intervening with coronary angiography, it turned out to be unremarkable for any coronary artery stenosis. She developed another episode of chest pain during her hospital stay with abnormal ECG patterns requiring further investigations with a non-invasive CT scan of coronary arteries and cardiac MRI for any infiltrative diseases. All workups were unremarkable. A multidisciplinary team involving the medical and interventional cardiology departments were involved in the diagnosis, and the patient was labeled as a case of vasospastic angina. She was treated with calcium channel blockers and was followed up as an outpatient for seven months with no further complications. Our main objective was to highlight the interesting phenomenon of Wellens and pseudo-Wellens syndrome. The condition requires early diagnosis and timely management to make sure that no underlying critical pathology is present that can result in fatal complications like MI or cardiac arrest.

摘要

心肌梗死(MI)是一种危急事件,需要及时诊断和迅速处理。如果不及时处理,Wellens综合征可能会进展为心肌梗死。它意味着心脏左前降支(LAD)动脉存在潜在的严重狭窄。在本报告中,我们讨论了一名高血压中年女性以非ST段抬高型心肌梗死(NSTEMI)病例入院时出现的假性Wellens综合征的有趣表现。在住院期间,她出现了一次伴有典型心电图改变的胸痛发作,提示Wellens综合征。然而,在进行冠状动脉造影检查时,结果显示冠状动脉没有任何狭窄。她在住院期间又出现了一次胸痛发作,心电图模式异常,需要进一步通过冠状动脉无创CT扫描和心脏MRI检查是否存在任何浸润性疾病。所有检查结果均无异常。一个由内科和介入心脏病学部门组成的多学科团队参与了诊断,该患者被诊断为血管痉挛性心绞痛。她接受了钙通道阻滞剂治疗,并作为门诊患者随访了七个月,没有出现进一步的并发症。我们的主要目的是强调Wellens综合征和假性Wellens综合征这一有趣现象。这种情况需要早期诊断和及时处理,以确保不存在可能导致心肌梗死或心脏骤停等致命并发症的潜在严重病变。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b9b3/7417120/e87623c04b92/cureus-0012-00000009116-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b9b3/7417120/22bffb97a589/cureus-0012-00000009116-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b9b3/7417120/0e03844f0c0a/cureus-0012-00000009116-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b9b3/7417120/e87623c04b92/cureus-0012-00000009116-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b9b3/7417120/22bffb97a589/cureus-0012-00000009116-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b9b3/7417120/0e03844f0c0a/cureus-0012-00000009116-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b9b3/7417120/e87623c04b92/cureus-0012-00000009116-i03.jpg

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本文引用的文献

1
Cocaine-induced pseudo-Wellens' syndrome: a Wellens' phenocopy.可卡因诱发的假性韦尔恩斯综合征:一种韦尔恩斯综合征的拟表型。
BMJ Case Rep. 2017 Dec 14;2017:bcr-2017-222835. doi: 10.1136/bcr-2017-222835.
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A special case of Wellens' syndrome.Wellens综合征的一种特殊情况。
J Cardiovasc Dis Res. 2013 Mar;4(1):51-4. doi: 10.1016/j.jcdr.2013.02.016. Epub 2013 Feb 27.
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Coronary artery spasm--clinical features, diagnosis, pathogenesis, and treatment.冠状动脉痉挛——临床特征、诊断、发病机制及治疗
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