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Testicular Adrenal Rest Tumour (TART) or Testicular Malignancy: A Clinical Dilemma.

作者信息

Roy Moni, Roy Ashish Kumar, Chatterjee Tulika, Bansal Saurabh

机构信息

Department of Internal Medicine, University of Illinois College of Medicine at Peoria and OSF Saint Francis Medical Center, Peoria, Illinois, USA.

出版信息

Eur J Case Rep Intern Med. 2020 May 8;7(8):001669. doi: 10.12890/2020_001669. eCollection 2020.

DOI:10.12890/2020_001669
PMID:32789136
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7417059/
Abstract

UNLABELLED

Testicular adrenal rest tumour (TART) is a known entity in patients with congenital adrenal hyperplasia. An adult patient presenting with testicular enlargement raises a concern for malignancy and this creates a diagnostic dilemma between non-malignant conditions such as TART versus testicular malignancy. We describe a case where the patient underwent orchiectomy due to clinical concern for malignancy but, retrospectively, this outcome could have been prevented by medical treatment. This case emphasises the need to learn from errors. There is a need to increase awareness of the condition among medical professionals to reduce the chances of unnecessary surgical intervention.

LEARNING POINTS

To recognize testicular adrenal rest tumour (TART) as cause of testicular enlargement in adult patients with congenital adrenal hyperplasia.To differentiate TART from other types of testicular malignancy.Consider medical treatment with exogenous glucocorticoid and mineralocorticoid replacement to prevent unnecessary surgical intervention.

摘要

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引用本文的文献

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Atypical Presentation of Testicular Adrenal Rest Tumor (TART) Leading to Bilateral Partial Orchiectomy in a 31-Year-Old Adult Revealing Primary Adrenal Insufficiency with Deficiency.睾丸肾上腺残余肿瘤(TART)的非典型表现导致一名31岁成年人双侧部分睾丸切除术,揭示原发性肾上腺皮质功能减退伴[此处原文缺失具体缺乏的内容]。
Case Rep Endocrinol. 2021 Dec 23;2021:5889007. doi: 10.1155/2021/5889007. eCollection 2021.

本文引用的文献

1
The High Prevalence of Testicular Adrenal Rest Tumors in Adult Men With Congenital Adrenal Hyperplasia Is Correlated With ACTH Levels.先天性肾上腺皮质增生成年男性睾丸肾上腺残余肿瘤的高患病率与促肾上腺皮质激素水平相关。
Front Endocrinol (Lausanne). 2019 Jun 4;10:335. doi: 10.3389/fendo.2019.00335. eCollection 2019.
2
Testicular Adrenal Rest Tumors: Current Insights on Prevalence, Characteristics, Origin, and Treatment.睾丸肾上腺残余肿瘤:患病率、特征、起源和治疗的最新见解。
Endocr Rev. 2019 Aug 1;40(4):973-987. doi: 10.1210/er.2018-00258.
3
Large testicular adrenal rest tumours in a patient with congenital adrenal hyperplasia.
一名先天性肾上腺皮质增生症患者的大型睾丸肾上腺残余肿瘤。
Endocrinol Diabetes Metab Case Rep. 2015;2015:140080. doi: 10.1530/EDM-14-0080. Epub 2015 Feb 1.
4
Testicular adrenal rest tumours in congenital adrenal hyperplasia.先天性肾上腺皮质增生症中的睾丸肾上腺残余瘤
Best Pract Res Clin Endocrinol Metab. 2009 Apr;23(2):209-20. doi: 10.1016/j.beem.2008.09.007.
5
Long term outcome in adult males with classic congenital adrenal hyperplasia.成年男性经典型先天性肾上腺皮质增生症的长期预后
J Clin Endocrinol Metab. 2001 Jul;86(7):3070-8. doi: 10.1210/jcem.86.7.7668.