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Oxygen-independent bactericidal systems. Mechanisms and disorders.

作者信息

Lehrer R I, Ganz T, Selsted M E

机构信息

Department of Medicine, UCLA School of Medicine.

出版信息

Hematol Oncol Clin North Am. 1988 Mar;2(1):159-69.

PMID:3279018
Abstract

Neutrophils contain microbicidal proteins packaged in numerous cytoplasmic granules. During phagocytosis, granules fuse to phagolysosomes where the granule contents contribute to the destruction and dissolution of ingested bacteria. The properties of the microbicidal proteins cathepsin G, BPI, and defensins are described and contrasted.

摘要

相似文献

1
Oxygen-independent bactericidal systems. Mechanisms and disorders.
Hematol Oncol Clin North Am. 1988 Mar;2(1):159-69.
2
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[Oxygen-independent microbicidal mechanisms of neutrophils].
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Microbicidal mechanisms of phagocytes.
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Preferential binding of the neutrophil cytoplasmic granule-derived bactericidal/permeability increasing protein to target bacteria. Implications and use as a means of purification.中性粒细胞胞质颗粒衍生的杀菌/通透性增加蛋白与靶细菌的优先结合。其意义及作为一种纯化手段的用途。
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6
Antibacterial proteins of granulocytes differ in interaction with endotoxin. Comparison of bactericidal/permeability-increasing protein, p15s, and defensins.粒细胞抗菌蛋白与内毒素的相互作用存在差异。杀菌/通透性增加蛋白、p15s和防御素的比较。
J Immunol. 1995 May 15;154(10):5403-10.
7
Antigonococcal activity of human neutrophil cathepsin G.人中性粒细胞组织蛋白酶G的抗淋球菌活性
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Disorders of stimulus-response coupling in neutrophils.中性粒细胞中刺激-反应偶联的紊乱。
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Am J Pathol. 1979 Mar;94(3):539-47.
10
Leukocyte-derived antimicrobial proteins.白细胞衍生的抗菌蛋白。
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