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局部应用硝酸甘油治疗血管升压药外周渗漏:一例报告

Topical nitroglycerin for management of peripheral extravasation of vasopressors: a case report.

作者信息

Shrestha Ninadini, Acharya Utsav, Shrestha Pramesh Sunder, Acharya Subhash Prasad, Karki Bipin, Dhakal Subodh Sagar

机构信息

Department of Anesthesiology, Institute of Medicine, Tribhuvan University Teaching Hospital, Kathmandu 44600, Nepal.

Department of Critical Care Medicine, Om Hospital and Research Centre, Kathmandu 44600, Nepal.

出版信息

Oxf Med Case Reports. 2020 Aug 10;2020(8):omaa066. doi: 10.1093/omcr/omaa066. eCollection 2020 Aug.

DOI:10.1093/omcr/omaa066
PMID:32793370
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7416830/
Abstract

Peripheral route for administration of vasopressors is often opted due to resource limitations or as a rescue until central venous access is established. This, however, is not devoid of complications, the most common being extravasation and tissue injury. Phentolamine is the only drug approved for management of vasopressor extravasation; however, successful use of other agents has been reported. Here we report a case of peripheral extravasation of vasopressors, successfully managed with topical nitroglycerin in intensive care unit in Kathmandu. To our knowledge, this is the first report of such kind from Nepal.

摘要

由于资源限制或作为建立中心静脉通路之前的一种抢救措施,血管加压药的外周给药途径经常被采用。然而,这并非没有并发症,最常见的是外渗和组织损伤。酚妥拉明是唯一被批准用于处理血管加压药外渗的药物;不过,也有使用其他药物成功的报道。在此,我们报告一例在加德满都重症监护病房外用硝酸甘油成功处理血管加压药外周外渗的病例。据我们所知,这是尼泊尔此类病例的首例报告。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/88f3/7416830/12df3845ad14/omaa066f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/88f3/7416830/1478b29c090a/omaa066f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/88f3/7416830/12df3845ad14/omaa066f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/88f3/7416830/1478b29c090a/omaa066f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/88f3/7416830/12df3845ad14/omaa066f2.jpg

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本文引用的文献

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Plast Reconstr Surg Glob Open. 2018 Apr 19;6(4):e1743. doi: 10.1097/GOX.0000000000001743. eCollection 2018 Apr.
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Alternative Pharmacological Management of Vasopressor Extravasation in the Absence of Phentolamine.在没有酚妥拉明的情况下对血管加压药外渗的替代药物治疗
P T. 2017 Sep;42(9):581-592.
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Pharmacotherapy. 2014 Jun;34(6):617-32. doi: 10.1002/phar.1396. Epub 2014 Jan 13.
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Extravasation injuries.外渗性损伤
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