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3只犬使用皮下注射特布他林和局部应用硝酸甘油软膏治疗外周血管收缩剂外渗的情况。

The use of injectable subcutaneous terbutaline and topical nitroglycerin ointment in the treatment of peripheral vasopressor extravasation in 3 dogs.

作者信息

Lathroum Chele N, Angulo Bracho Hernan Lizardo, Alessandrino Kayla M, Walker Julie M

机构信息

Department of Medical Sciences, School of Veterinary Medicine, University of Wisconsin-Madison, Madison, Wisconsin, USA.

Gulf Coast Veterinary Specialists, Houston, Texas, USA.

出版信息

J Vet Emerg Crit Care (San Antonio). 2024 Jul-Aug;34(4):393-398. doi: 10.1111/vec.13393. Epub 2024 Jun 20.

DOI:10.1111/vec.13393
PMID:39031632
Abstract

OBJECTIVE

To describe the clinical course and treatment of 3 dogs with peripheral vasopressor extravasation.

CASE SERIES SUMMARY

Although vasopressor extravasation (VE) is a well-documented complication in human medicine, literature describing VE and its management in veterinary patients is sparse. VE increases patient morbidity by causing local tissue injury and necrosis. The gold standard treatment for VE, phentolamine, has been periodically limited in supply in human medicine and is not consistently available for use in veterinary medicine. An alternative protocol proposed for use in people with VE combines topical nitroglycerin application with subcutaneous terbutaline infiltration. In this report, a treatment protocol utilizing these therapies was used to treat 3 dogs with VE and secondary tissue injury.

NEW OR UNIQUE INFORMATION PROVIDED

This report describes 3 cases of VE-induced tissue injury in dogs. In addition, this report describes the use of perivascular terbutaline infiltration and topical nitroglycerin application as therapeutic management for VE in dogs.

摘要

目的

描述3例患有外周血管收缩剂外渗的犬的临床病程及治疗情况。

病例系列总结

尽管血管收缩剂外渗(VE)在人类医学中是一种有充分文献记载的并发症,但描述兽医患者VE及其处理的文献却很稀少。VE通过引起局部组织损伤和坏死增加患者发病率。VE的金标准治疗药物酚妥拉明在人类医学中的供应有时会受到限制,并且在兽医学中并非始终可用。一种提议用于VE患者的替代方案是将局部应用硝酸甘油与皮下注射特布他林相结合。在本报告中,采用了利用这些疗法的治疗方案来治疗3例患有VE和继发性组织损伤的犬。

提供的新的或独特信息

本报告描述了3例犬因VE导致的组织损伤病例。此外,本报告描述了血管周围注射特布他林和局部应用硝酸甘油作为犬VE治疗管理方法的应用情况。

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