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食管癌手术后的乳糜漏

Chyle Leakage after Esophageal Cancer Surgery.

作者信息

Yang Young Ho, Park Seong Yong, Kim Dae Joon

机构信息

Department of Thoracic and Cardiovascular Surgery, Yonsei University College of Medicine, Seoul, Korea.

出版信息

Korean J Thorac Cardiovasc Surg. 2020 Aug 5;53(4):191-199. doi: 10.5090/kjtcs.2020.53.4.191.

DOI:10.5090/kjtcs.2020.53.4.191
PMID:32793451
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7409880/
Abstract

Surgeons recommend dissecting lymph nodes in the thorax, abdomen, and neck during surgery for esophageal cancer because of the possibility of metastasis to the lymph nodes in those areas through the lymphatic plexus of the esophageal submucosal layer. Extensive lymph node dissection is essential for accurate staging and is thought to improve survival. However, it can result in several complications, including chyle leakage, which refers to continuous lymphatic fluid leakage and can occur in the thorax, abdomen, and neck. Malnutrition, fluid imbalance, and immune compromise may result from chyle leakage, which can be potentially life-threatening if it persists. Therefore, various treatment methods, including conservative treatment, pharmacological treatment such as octreotide infusion, and interventions such as thoracic duct embolization and surgical thoracic duct ligation, have been applied. In this article, the risk factors, diagnosis, and treatment methods of chyle leakage after esophagectomy are reviewed.

摘要

由于食管癌有可能通过食管黏膜下层的淋巴丛转移至胸部、腹部和颈部的淋巴结,外科医生建议在食管癌手术期间对这些部位的淋巴结进行清扫。广泛的淋巴结清扫对于准确分期至关重要,并且被认为可以提高生存率。然而,它可能导致多种并发症,包括乳糜漏,即淋巴液持续漏出,可发生于胸部、腹部和颈部。乳糜漏可能导致营养不良、液体失衡和免疫功能受损,如果持续存在,可能会危及生命。因此,已经应用了各种治疗方法,包括保守治疗、诸如注射奥曲肽的药物治疗以及诸如胸导管栓塞和胸导管手术结扎等干预措施。在本文中,对食管切除术后乳糜漏的危险因素、诊断和治疗方法进行了综述。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/47ec/7409880/4b5173e0a16a/KJTCV-53-191-f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/47ec/7409880/585c3ac38e7e/KJTCV-53-191-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/47ec/7409880/4b5173e0a16a/KJTCV-53-191-f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/47ec/7409880/585c3ac38e7e/KJTCV-53-191-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/47ec/7409880/4b5173e0a16a/KJTCV-53-191-f2.jpg

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本文引用的文献

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Risk factors of chylothorax after esophagectomy.食管切除术后乳糜胸的危险因素。
J Thorac Dis. 2019 May;11(5):1749-1752. doi: 10.21037/jtd.2019.05.17.
2
Negative Pressure Wound Therapy (Wound VAC) in the Treatment of Chylous Fistula After Neck Dissection.负压伤口治疗(伤口负压封闭引流)在颈部清扫术后乳糜瘘治疗中的应用
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Low-Dose Radiation Therapy is an Effective Treatment for Refractory Postoperative Chylous Ascites: A Case Report.
肌少症会降低食管癌机器人食管切除术后的总生存率。
Sci Rep. 2025 May 5;15(1):15726. doi: 10.1038/s41598-025-00058-7.
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Induction Radiochemotherapy for Esophageal Cancer: Long-Term Outcomes from a Single-Center Study.食管癌的诱导放化疗:一项单中心研究的长期结果
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Metastatic patterns of subcarinal, right and left recurrent laryngeal nerve lymph nodes in thoracic esophageal squamous cell carcinoma without neoadjuvant therapy.未经新辅助治疗的胸段食管鳞癌的隆突下、右和左喉返神经淋巴结转移模式。
J Cancer Res Clin Oncol. 2024 Aug 7;150(8):387. doi: 10.1007/s00432-024-05911-2.
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Management of a decade-old recurrent chylothorax with breast fistulization: a case report.伴有乳房瘘管形成的十年复发性乳糜胸的治疗:一例报告
AME Case Rep. 2024 Jan 4;8:24. doi: 10.21037/acr-23-157. eCollection 2024.
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Indocyanine green dye and its application in gastrointestinal surgery: The future is bright green.吲哚菁绿染料及其在胃肠外科手术中的应用:未来一片翠绿。
World J Gastrointest Surg. 2023 Sep 27;15(9):1841-1857. doi: 10.4240/wjgs.v15.i9.1841.
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Am J Case Rep. 2023 Jul 17;24:e938611. doi: 10.12659/AJCR.938611.
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Postesophagectomy chylothorax: a review of the risk factors, diagnosis, and management.食管切除术后乳糜胸:危险因素、诊断及治疗综述
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Thorac Cardiovasc Surg. 2018 Aug;66(5):370-375. doi: 10.1055/s-0037-1602259. Epub 2017 May 2.
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Selective En Masse Ligation of the Thoracic Duct to Prevent Chyle Leak After Esophagectomy.选择性胸导管整块结扎术预防食管癌切除术后乳糜漏
Ann Thorac Surg. 2017 Jun;103(6):1802-1807. doi: 10.1016/j.athoracsur.2017.01.025. Epub 2017 Apr 3.