Cho Jong Ho
Department of Thoracic and Cardiovascular Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Korean J Thorac Cardiovasc Surg. 2020 Aug 5;53(4):217-221. doi: 10.5090/kjtcs.2020.53.4.217.
Gastroesophageal reflux is a common problem after gastroesophageal resection and reconstruction, despite the routine prescription of proton pump inhibitors (PPIs). Resection of the lower esophageal sphincter and excision of the vagus nerve are generally thought to be the main factors that interfere with gastric motor function. However, physiological studies of reflux symptoms after esophagectomy are still lacking. Gastroesophageal reflux occurs frequently after esophagectomy, but there is no known effective method to prevent it. Therefore, in order to manage gastroesophageal reflux after esophagectomy, strict lifestyle modifications and gastric acid suppression treatment such as PPIs are needed, and further clinical studies are required.
尽管常规使用质子泵抑制剂（PPI），但胃食管反流仍是胃食管切除重建术后的常见问题。食管下括约肌切除和迷走神经切断通常被认为是干扰胃运动功能的主要因素。然而，目前仍缺乏对食管切除术后反流症状的生理学研究。食管切除术后胃食管反流频繁发生，但尚无已知的有效预防方法。因此，为了处理食管切除术后的胃食管反流，需要严格改变生活方式并进行胃酸抑制治疗，如使用PPI，并且还需要进一步的临床研究。
