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COVID-19 皮肤表现的家族聚集性。

Familial clustering of COVID-19 skin manifestations.

机构信息

Department of Dermatology, "St. Parascheva" Clinical Hospital of Infectious Diseases, Galati, Romania.

Faculty of Medicine and Pharmacy/Clinical Department, Dermatology, Medical, and Pharmaceutical Research Unit/Competitive, Interdisciplinary Research Integrated Platform, ReForm-UDJG "Dunărea de Jos" University, Galati, Romania.

出版信息

Dermatol Ther. 2020 Nov;33(6):e14181. doi: 10.1111/dth.14181. Epub 2020 Sep 4.

Abstract

The medical community in the past months has seen a flourishing of information related to the SARS-CoV-2 virus responsible for the COVID-19 pandemic. From the early days of the pandemic, the SARS-CoV-2 virus has been linked to multiple different types of skin involvement. To the best of our knowledge, we are the first to report on a case of familial clustering of a maculopapular COVID-19 rash. Eight persons presented COVID-19 symptoms, six were confirmed via SAR-CoV-2 chemoluminescent immunoassays, and the four related by blood presented skin manifestations. Although, it has not been fully established if the SARS-CoV-2 can in fact cause viral exanthems, our observations regarding the familial clustering and the temporal evolution seen in this family seem to present strong evidence of a viral exanthema related to SARS-CoV-2 infection.

摘要

在过去的几个月里,医学界看到了与导致 COVID-19 大流行的 SARS-CoV-2 病毒相关的大量信息。从大流行早期开始,SARS-CoV-2 病毒就与多种不同类型的皮肤受累有关。据我们所知,我们是第一个报告 COVID-19 皮疹家族聚集的病例。八个人出现了 COVID-19 症状,六个人通过 SAR-CoV-2 化学发光免疫分析得到确认,并且四个有血缘关系的人出现了皮肤表现。虽然尚未完全确定 SARS-CoV-2 是否实际上会导致病毒性发疹,但我们对该家族中观察到的家族聚集和时间演变的观察结果似乎提供了与 SARS-CoV-2 感染相关的病毒性发疹的有力证据。

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