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新冠感染后精神病:严重急性呼吸综合征冠状病毒2(SARS-CoV-2)病毒感染会是引发精神障碍的一种神经精神疾病吗?——基于病例的简短综述

Post COVID-19 Infection Psychosis: Could SARS-CoV-2 Virus Infection Be a Neuropsychiatric Condition That Triggers Psychotic Disorders? - A Case-Based Short Review.

作者信息

Vasile Claudiu Ionut, Vasile Mihaela Camelia, Zlati Monica Laura, Herbei Elena Emanuela, Lepădatu Lorena, Munteanu Cristina, Nechifor Alexandru, Tatu Alin Laurențiu

机构信息

Clinical Medical Department, Faculty of Medicine and Pharmacy, "Dunărea de Jos" University, Galați, România.

"Elena Doamna" Clinical Hospital of Psychiatry, Galaţi, România.

出版信息

Infect Drug Resist. 2022 Aug 22;15:4697-4705. doi: 10.2147/IDR.S373578. eCollection 2022.

Abstract

Corona virus (COVID-19) is an epidemy of respiratory disease caused by a novel corona virus and it was declared by the World Health Organization (WHO) to be a global health pandemic emergency. Due to the neuropsychiatric manifestation of Covid-19 that have been associated with psychotic disorders, in this paper we choose to present a case from "Elena Doamna" Psychiatric Hospital from Galati, Romania and to correlate it with other cases from literature in a mini review presentation. In our paper, we present the case of a patient of 44-year-old men, with no past psychiatric history whose behavior included psycho-motor agitation, perception and thinking disorders, disorganized behaviour, attempted suicide by stabbing. The last perspectives from the two years of pandemic together with psychiatric disease linked the virus infections with psychosis to the main concern that Covid-19 could determine psychiatric disorders. There were also presented same literature studies of patients with no personal pathological history in the psychiatric field which developed psychiatric disorders after COVID-19 infection. SARS-CoV-2 has a psychological impact on the mental health status of the worldwide and, especially when it is associated with psychotic symptoms and can affect the quality-of-life. In some cases, the virus affected the brain and as a result, the psychosis symptoms could be an emerging phenomenon associated with the corona virus. Based on the DSM V and ICD-10 criteria, the diagnosis was of acute psychiatric disorders with symptoms of schizophrenia (F23.1). The case report and review reliefs that there is a causal link between the SARS CoV-2 infection and mental disorders, which is currently being investigated.

摘要

冠状病毒(COVID-19)是一种由新型冠状病毒引起的呼吸道疾病流行病,世界卫生组织(WHO)宣布其为全球卫生大流行紧急情况。由于COVID-19的神经精神表现与精神障碍有关,在本文中,我们选择介绍罗马尼亚加拉茨“埃琳娜夫人”精神病院的一个病例,并在一个小型综述介绍中将其与文献中的其他病例进行关联。在我们的论文中,我们介绍了一名44岁男性患者的病例,他既往无精神病史,其行为包括精神运动性激越、感知和思维障碍、行为紊乱、刺伤企图自杀。大流行两年以来的最新观点以及精神疾病将病毒感染与精神病联系起来,这主要是因为人们担心COVID-19可能导致精神障碍。还介绍了一些精神病学领域无个人病理史的患者在感染COVID-19后出现精神障碍的文献研究。SARS-CoV-2对全球心理健康状况有心理影响,尤其是当它与精神病症状相关时,会影响生活质量。在某些情况下,病毒会影响大脑,因此,精神病症状可能是与冠状病毒相关的一种新出现的现象。根据《精神疾病诊断与统计手册》第五版(DSM V)和《国际疾病分类》第十版(ICD-10)标准,诊断为伴有精神分裂症症状的急性精神障碍(F23.1)。该病例报告和综述表明,SARS-CoV-2感染与精神障碍之间存在因果关系,目前正在对此进行调查。

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本文引用的文献

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COVID-19-associated psychosis: A systematic review of case reports.COVID-19 相关精神病:病例报告的系统回顾。
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Psychosis as an adverse effect of antibiotics.精神病作为抗生素的一种不良反应。
Brain Behav Immun Health. 2020 Sep 19;9:100148. doi: 10.1016/j.bbih.2020.100148. eCollection 2020 Dec.
9
COVID-19 and psychosis risk: Real or delusional concern?COVID-19 与精神病风险:真实还是妄想?
Neurosci Lett. 2021 Jan 10;741:135491. doi: 10.1016/j.neulet.2020.135491. Epub 2020 Nov 18.

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