Jordan P H, Morrow C
Cora and Webb Mading Department of Surgery, Baylor College of Medicine, Houston, Texas.
Surg Clin North Am. 1988 Apr;68(2):315-29. doi: 10.1016/s0039-6109(16)44480-4.
Peptic ulcer disease has declined significantly since 1950 in industrialized nations. However, the number of patients with perforated and bleeding ulcers has been constant or has declined only slightly, except for older patients, in whom the frequency has increased. In patients with perforated ulcers, operative management is preferable to non-operative treatment. The operative choices are simple closure of the perforation or definitive surgery. Patients who have significant risk factors should undergo simple closure. Closure of the ulcer with parietal cell vagotomy is the author's first choice for definitive operative treatment when this procedure can be performed.
自1950年以来，工业化国家的消化性溃疡疾病显著减少。然而，除老年患者（其发病率有所增加）外，穿孔性和出血性溃疡患者的数量一直保持稳定或仅略有下降。对于穿孔性溃疡患者，手术治疗优于非手术治疗。手术选择包括单纯穿孔闭合术或确定性手术。有显著危险因素的患者应接受单纯闭合术。当可以进行壁细胞迷走神经切断术时，作者首选该术式作为确定性手术治疗来闭合溃疡。
