Burch P A, Grossman S A
Johns Hopkins University School of Medicine, Johns Hopkins Hospital, Baltimore, Maryland.
Am J Med. 1988 Mar;84(3 Pt 1):555-8. doi: 10.1016/0002-9343(88)90284-7.
Epidural cord compressions are a frequent and serious problem for patients with cancer. Standard treatment for these lesions includes local irradiation with or without surgery. Herein are reported two cases of epidural cord compression from Hodgkin's disease that responded dramatically to systemic chemotherapy. A review of the literature reveals reports of successful chemotherapy in the treatment of seven patients with epidural metastases secondary to lymphomas and 15 secondary to a variety of other tumors. The use of systemic chemotherapy is an increasingly important therapeutic option for treatment of epidural cord compressions in carefully selected patients.
硬膜外脊髓压迫对癌症患者来说是一个常见且严重的问题。这些病变的标准治疗方法包括局部放疗，可联合或不联合手术。本文报告了两例霍奇金病导致的硬膜外脊髓压迫病例，对全身化疗反应显著。文献回顾显示，有关于化疗成功治疗7例淋巴瘤继发硬膜外转移患者以及15例其他各种肿瘤继发硬膜外转移患者的报道。对于经过精心挑选的患者，全身化疗日益成为治疗硬膜外脊髓压迫的重要治疗选择。
