Penas-Prado Marta, Loghin Monica E
Department of Neuro-Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Box 431, Houston, TX 77030, USA.
Curr Oncol Rep. 2008 Jan;10(1):78-85. doi: 10.1007/s11912-008-0012-0.
Spinal cord compression (SCC) is a well-known complication in cancer patients, with an enormous potential impact on quality of life. In most cases, treatment is palliative, but a prompt diagnosis and immediate treatment is essential to preserving neurological function. Whereas steroids and radiation have been the mainstay of therapy for many years, the role and timing of surgery has remained controversial. However, class I evidence now exists to support the benefit of pre-irradiation surgical decompression in a carefully selected subpopulation of patients with SCC. A multidisciplinary approach is required to maximize the therapeutic and functional outcome of these patients.
脊髓压迫症（SCC）是癌症患者中一种广为人知的并发症，对生活质量有极大的潜在影响。在大多数情况下，治疗是姑息性的，但及时诊断和立即治疗对于保留神经功能至关重要。多年来，类固醇和放疗一直是主要的治疗手段，而手术的作用和时机仍存在争议。然而，现在有I类证据支持在精心挑选的SCC患者亚群中进行放疗前手术减压的益处。需要采用多学科方法来使这些患者的治疗和功能结果最大化。
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