Ahmad Nehad J, Althemery Abdullah U, Haseeb Abdul, Yusuf Reham F, Hassali Azmi Ahmed, Khan Amer H
Discipline of Clinical Pharmacy, School of Pharmaceutical Sciences, Universiti Sains Malaysia, George Town, Penang, Malaysia.
Clinical Pharmacy Department, College of Pharmacy, Prince Sattam Bin Abdulaziz University, Al-Kharj, Saudi Arabia.
J Pharm Bioallied Sci. 2020 Jan-Mar;12(1):11-15. doi: 10.4103/jpbs.JPBS_186_19. Epub 2020 Jan 29.
The implementation of antibiotic stewardship programs (ASPs) can improve the treatment of infections and can decrease the adverse events that result from antibiotics use. In the last decades, there is an increasing interest of the researchers in the implementation of ASPs.
The articles published in different journals were retrieved by searching many research databases such as Cochrane library, Europe PMC, PubMed, and Web of Science; we searched these databases for all published articles till November 2018.
The searching results using Cochrane library showed an increase in the number of randomized clinical trials that related to the keyword of "antimicrobial stewardship" specially in the last 5 years. Using Europe PMC, we found 6178 results. From these results, there are 3874 free full texts. In addition, there are 2132 original articles in PubMed and by searching Web of Science database till November 8 there are 3085 results. These results show that the number of trusted published articles was increased continuously; this shows the increasing interest of the researchers in ASPs. These researches will help health-care providers to use antibiotics appropriately and to overcome the barriers of implementing ASPs.
The results of this study show that the researchers had high levels of interest in participating in research activities related to the appropriate use on antibiotics and the implementation of antimicrobial stewardship programs.
抗生素管理计划（ASPs）的实施可以改善感染治疗，并减少抗生素使用导致的不良事件。在过去几十年中，研究人员对实施ASPs的兴趣日益增加。
通过搜索多个研究数据库（如Cochrane图书馆、欧洲PMC、PubMed和科学网）检索不同期刊上发表的文章；我们在这些数据库中搜索截至2018年11月所有已发表的文章。
使用Cochrane图书馆的搜索结果显示，与“抗菌药物管理”关键词相关的随机临床试验数量有所增加，特别是在过去5年。使用欧洲PMC，我们找到了6178条结果。从这些结果中，有3874篇免费全文。此外，PubMed中有2132篇原创文章，截至11月8日搜索科学网数据库有3085条结果。这些结果表明，可信发表文章的数量持续增加；这表明研究人员对ASPs的兴趣日益增加。这些研究将帮助医疗保健提供者合理使用抗生素，并克服实施ASPs的障碍。
本研究结果表明，研究人员对参与与抗生素合理使用和抗菌药物管理计划实施相关的研究活动有很高的兴趣。
