Sadasivan Arun, Ramesh Roshni, Kurien Nikhil M
Department of Periodontics, Sree Mookambika Institute of Dental Sciences, Kulashekaram, Tamil Nadu, India.
Department of Periodontics, Government Dental College, Thrissur, Kerala, India.
Clin Cosmet Investig Dent. 2020 Jul 21;12:297-304. doi: 10.2147/CCIDE.S261308. eCollection 2020.
Adenomatoid odontogenic tumor (AOT) is an uncommon benign odontogenic lesion with varied clinical and histological presentation. It has slow growth potential and a low recurrence rate. The tumor is mainly seen in females in the second decade of life, predominantly affecting the maxilla and associated most often with unerupted canine teeth, earning the epithet "two-thirds tumor". There are three variants: intrafollicular, extrafollicular, and peripheral. The peripheral or extra osseous type is a rare form that arises in gingival tissue.
This article describes a case of AOT in a 10-year-old girl who presented with gingival enlargement in relation to the maxillary left central incisor. Interestingly, intraoral periapical radiography did not show any significant findings. However, cone-beam computed tomography of the site revealed significant bone loss in the area. A surgical excision was done. Histopathological examination revealed features of AOT. Based on clinical, radiographic, and histological evidence, a diagnosis of peripheral AOT (PAOT) was made.
PAOT is a rare disease entity in children that mimics gingival swelling, and may often be misdiagnosed by dentists. With literature still ambiguous on the origin of the tumor and biological course, it becomes imperative to examine any gingival swelling in children with a proper clinical examination, periapical radiography, and if necessary cone-beam computed tomography. Excision and histopathological evaluation will help in confirming the exact disease condition.
腺样牙源性肿瘤(AOT)是一种罕见的良性牙源性病变,具有多种临床和组织学表现。它生长缓慢,复发率低。该肿瘤主要见于20岁左右的女性,主要累及上颌骨,最常与未萌出的尖牙相关,因此有“三分之二肿瘤”这一别称。有三种变体:滤泡内型、滤泡外型和周边型。周边型或骨外型是一种罕见的类型,发生于牙龈组织。
本文描述了一名10岁女孩的腺样牙源性肿瘤病例,该女孩因上颌左中切牙处牙龈肿大就诊。有趣的是,口腔根尖片未显示任何明显异常。然而,该部位的锥形束计算机断层扫描显示该区域有明显的骨质流失。进行了手术切除。组织病理学检查显示腺样牙源性肿瘤的特征。根据临床、影像学和组织学证据,诊断为周边型腺样牙源性肿瘤(PAOT)。
周边型腺样牙源性肿瘤(PAOT)在儿童中是一种罕见的疾病实体,表现为牙龈肿胀,常被牙医误诊。由于关于该肿瘤的起源和生物学过程的文献仍不明确,因此对儿童的任何牙龈肿胀进行适当的临床检查、根尖片检查,必要时进行锥形束计算机断层扫描就变得至关重要。切除并进行组织病理学评估将有助于确诊确切的疾病情况。