Yao Fang, Zhang Yang, Kuang Xiaohong, Zhou Qi, Huang Lihua, Peng Jiazhu, Du Shizheng
Department of Nursing, Zhangjiagang TCM Hospital Affiliated to Nanjing University of Chinese Medicine, Suzhou, China.
School of Nursing, Nanjing University of Traditional Chinese Medicine, Nanjing, China.
Evid Based Complement Alternat Med. 2020 Jul 29;2020:8645727. doi: 10.1155/2020/8645727. eCollection 2020.
This study aimed to evaluate the effects and safety of moxibustion in the management of constipation.
Constipation is extremely common in clinical practice and causes physical and mental pain to patients. This study aimed to evaluate the effects and safety of moxibustion in the management of constipation.
Studies on moxibustion for constipation published up to November 2019 were searched in PubMed; EBSCO; EMBASE; Cochrane Library; and three Chinese databases, namely, China National Knowledge Internet, Wanfang, and China Biomedical Network. The methodological quality of the included studies was assessed on the basis of the CLEAR NPT system evaluation methods of Boutron. Further meta-analysis was performed using the RevMan 5.3 and Stata 15.0 software.
Ten randomized controlled trials involving 760 patients were included in this study. The meta-analysis revealed that, in comparison to western medicine treatment or other Chinese medicine methods (control group), moxibustion (experimental group) had a higher total effective rate (RR = 1.30, 95% CI [1.21, 1.40], < 0.00001), and the clinical effectiveness of the experimental group was higher than that of the control group in any subgroup analysis. The first defecation time of the experimental group was shorter than that of the control group (SMD = -1.36, 95% CI [-2.03, -0.68], < 0.0001). The clinical symptom score of the patients in the experimental group was lower than that in the control group (SMD = -0.65, 95% CI [-1.00, -0.30], =0.0003). The patients in the experimental group had higher scores on Bristol stool form scale than those in the control group (MD = 0.99, 95% CI [0.48, 1.50], =0.0001). However, there was no obvious difference in safety between the two groups (RR = 0.38, 95% CI [0.01, 11.8], =0.58).
Moxibustion may have better effect than other treatments on constipation. However, it is not yet possible to assess the safety level of moxibustion therapy, and the quality of the included literature is low, so rigorous studies are warranted. . The focus of this study was to evaluate the effectiveness and safety of moxibustion therapy in constipation. This evaluation showed that moxibustion therapy has a good effect on constipation and provides an effective treatment for constipation patients. Whether moxibustion therapy can be used for different syndrome types deserves further discussion.
本研究旨在评估艾灸治疗便秘的效果及安全性。
便秘在临床实践中极为常见，给患者带来身心痛苦。本研究旨在评估艾灸治疗便秘的效果及安全性。
检索截至2019年11月在PubMed、EBSCO、EMBASE、Cochrane图书馆以及三个中文数据库（中国知网、万方和中国生物医学网络）上发表的关于艾灸治疗便秘的研究。根据Boutron的CLEAR NPT系统评估方法对纳入研究的方法学质量进行评估。使用RevMan 5.3和Stata 15.0软件进行进一步的荟萃分析。
本研究纳入了10项涉及760例患者的随机对照试验。荟萃分析显示，与西医治疗或其他中医方法（对照组）相比，艾灸（试验组）的总有效率更高（RR = 1.30，95%CI [1.21, 1.40]，P < 0.00001），并且在任何亚组分析中试验组的临床疗效均高于对照组。试验组的首次排便时间短于对照组（SMD = -1.36，95%CI [-2.03, -0.68]，P < 0.0001）。试验组患者的临床症状评分低于对照组（SMD = -0.65，95%CI [-1.00, -0.30]，P = 0.0003）。试验组患者的布里斯托大便分类法评分高于对照组（MD = 0.99，95%CI [0.48, 1.50]，P = 0.0001）。然而，两组之间的安全性无明显差异（RR = 0.38，95%CI [0.01, 11.8]，P = 0.58）。
艾灸治疗便秘可能比其他治疗方法效果更好。然而，目前尚无法评估艾灸疗法的安全水平，且纳入文献的质量较低，因此需要进行严谨的研究。本研究的重点是评估艾灸疗法治疗便秘的有效性和安全性。该评估表明艾灸疗法对便秘有良好效果，为便秘患者提供了一种有效的治疗方法。艾灸疗法是否可用于不同证型值得进一步探讨。
