Chen Ying, Xu Mingmin, Hou Tinghui, Wang Lu, Feng Xiumei, Li Ying
School of Acupuncture and Moxibustion and Tuina, Chengdu University of Traditional Chinese Medicine. No. 37 Shierqiao Road, Jinniu District, Chengdu, Sichuan, China.
Medicine (Baltimore). 2020 Jul 10;99(28):e20910. doi: 10.1097/MD.0000000000020910.
The objective of this review is to assess the efficacy and safety of moxibustion for treating patients with functional constipation (FC).
We will electronically search the following databases: OVID MEDLINE, EMBASE, PubMed, Web of Science, the Cochrane Central Register of Controlled Trials, Cochrane library, CINAHL, AMED, China Network Knowledge Infrastructure, Wan-fang Database, China Biomedical Literature Database, and other resources from inception to October 2019, without any language restrictions. Randomised-controlled trials will be included. The primary outcome is the improvement in mean complete spontaneous bowel movements and stool form (utilize the Bristol Stool Form Scale [BSFS]). Secondary outcomes involve the degree of difficulty in defecation, proportion of responders, mean transit time, health-related quality of life, and adverse events rate. The methodological quality will be assessed using the Cochrane risk of bias tool.
This work will summarize clinical evidence to assess the effectiveness and safety of moxibustion treatment for FC patients.
This systematic review and meta-analysis will provide current evidence of the efficacy and safety of moxibustion treating FC.
PROSPERO, CRD42020157955.
本综述的目的是评估艾灸治疗功能性便秘（FC）患者的疗效和安全性。
我们将通过电子检索以下数据库：OVID MEDLINE、EMBASE、PubMed、Web of Science、Cochrane对照试验中央注册库、Cochrane图书馆、CINAHL、AMED、中国知网、万方数据库、中国生物医学文献数据库以及其他资源，检索时间从建库至2019年10月，无任何语言限制。将纳入随机对照试验。主要结局是平均完全自主排便次数和粪便形态的改善（采用布里斯托粪便形态量表[BSFS]）。次要结局包括排便困难程度、有效应答者比例、平均传输时间、健康相关生活质量以及不良事件发生率。将使用Cochrane偏倚风险工具评估方法学质量。
本研究将总结临床证据，以评估艾灸治疗FC患者的有效性和安全性。
本系统评价和荟萃分析将提供艾灸治疗FC疗效和安全性的当前证据。
PROSPERO，CRD42020157955。
