Faculty of Medicine, Clinical Laboratory, PCR Unit, Kocaeli University, Kocaeli, Turkey.
DESAM Institute, Near East University, Nicosia/TRNC, Mersin-10, 99138, Turkey.
Comput Math Methods Med. 2020 Aug 6;2020:1560250. doi: 10.1155/2020/1560250. eCollection 2020.
In December 2019, cases of pneumonia were detected in Wuhan, China, which were caused by the highly contagious coronavirus. This study is aimed at comparing the confusion regarding the selection of effective diagnostic methods to make a mutual comparison among existing SARS-CoV-2 diagnostic tests and at determining the most effective one. Based on available published evidence and clinical practice, diagnostic tests of coronavirus disease (COVID-19) were evaluated by multi-criteria decision-making (MCDM) methods, namely, fuzzy preference ranking organization method for enrichment evaluation (fuzzy PROMETHEE) and fuzzy technique for order of preference by similarity to ideal solution (fuzzy TOPSIS). Computerized tomography of chest (chest CT), the detection of viral nucleic acid by polymerase chain reaction, cell culture, CoV-19 antigen detection, CoV-19 antibody IgM, CoV-19 antibody IgG, and chest X-ray were evaluated by linguistic fuzzy scale to compare among the diagnostic tests. This scale consists of selected parameters that possessed different weights which were determined by the experts' opinions of the field. The results of our study with both proposed MCDM methods indicated that the most effective diagnosis method of COVID-19 was chest CT. It is interesting to note that the methods that are consistently used in the diagnosis of viral diseases were ranked in second place for the diagnosis of COVID-19. However, each country should use appropriate diagnostic solutions according to its own resources. Our findings also show which diagnostic systems can be used in combination.
2019 年 12 月,中国武汉发现了由高传染性冠状病毒引起的肺炎病例。本研究旨在比较在选择有效诊断方法时的困惑,以便对现有的 SARS-CoV-2 诊断检测方法进行相互比较,并确定最有效的方法。根据现有发表的证据和临床实践,采用多准则决策 (MCDM) 方法评估了冠状病毒病 (COVID-19) 的诊断测试,即模糊偏好排序组织法的富集评价 (模糊 PROMETHEE) 和偏好排序技术相似理想解 (模糊 TOPSIS)。计算机断层扫描 (chest CT)、聚合酶链反应检测病毒核酸、细胞培养、CoV-19 抗原检测、CoV-19 抗体 IgM、CoV-19 抗体 IgG 和胸部 X 射线通过语言模糊量表进行评估,以比较诊断测试。该量表包含不同权重的选定参数,这些权重是由该领域专家的意见确定的。这两种 MCDM 方法的研究结果均表明,COVID-19 的最有效诊断方法是 chest CT。有趣的是,在病毒性疾病诊断中一直使用的方法在 COVID-19 诊断中排名第二。然而,每个国家都应根据自身资源使用适当的诊断解决方案。我们的研究结果还表明,哪些诊断系统可以联合使用。