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临床中酒渣鼻的管理:从病理生理学到治疗——文献综述

Managing Rosacea in the Clinic: From Pathophysiology to Treatment-A Review of the Literature.

作者信息

Johnson Sandra Marchese, Berg Andrew, Barr Chelsea

机构信息

Dr. Johnson is with Johnson Dermatology in Fort Smith, Arkansas.

Mr. Berg is with Dermatology Specialists of Kansas City in Kansas City, Missouri; and.

出版信息

J Clin Aesthet Dermatol. 2020 Apr;13(4 Suppl):S17-S22. Epub 2020 Apr 1.

Abstract

Rosacea is a chronic skin disease characterized by a waxing and waning course. It can encompass different symptoms including erythema, papules/pustules, telangiectasia, and phymata and sometimes secondary manifestations, such as itching, burning, or stinging. This article reviews recent changes in rosacea management. Discussion of relevant medical literature augmented with clinical expertise is also provided. Notably, while patients report that rosacea negatively impacts their emotional and overall well-being, they also tend to have low satisfaction with treatment and are prone to discontinuing therapy and/or using rosacea medications on an intermittent basis, thereby undermining treatment efficacy. Fortunately, the therapeutic armamentarium for rosacea is expanding, and experts now recommend a treatment approach that targets the presenting signs and/or symptoms, with the goal of achieving the greatest possible clearance. More so than in the past, several treatments can be used concurrently to best address the overall presentation of rosacea in an individual patient.

摘要

酒渣鼻是一种慢性皮肤病,其病程呈反复消长。它可表现为多种不同症状,包括红斑、丘疹/脓疱、毛细血管扩张和鼻赘,有时还伴有继发性表现,如瘙痒、灼痛或刺痛。本文回顾了酒渣鼻治疗方面的近期变化。同时还结合临床专业知识对相关医学文献进行了讨论。值得注意的是,虽然患者报告酒渣鼻对他们的情绪和整体健康有负面影响,但他们对治疗的满意度往往较低,并且容易间断治疗和/或间歇性使用治疗酒渣鼻的药物,从而影响治疗效果。幸运的是,治疗酒渣鼻的手段正在不断增加,现在专家们推荐一种针对当前出现的体征和/或症状的治疗方法,目标是尽可能实现最大程度的清除。与过去相比,现在可以同时使用多种治疗方法,以更好地应对个体患者酒渣鼻的整体表现。

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Psychosocial aspects of rosacea with a focus on anxiety and depression.酒渣鼻的社会心理因素,重点关注焦虑和抑郁
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Successful therapy of ocular rosacea with topical ivermectin.局部用伊维菌素成功治疗眼部酒渣鼻。
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Shortcomings in rosacea diagnosis and classification.酒渣鼻诊断与分类中的不足。
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