Solway Jason, McBride Michael, Haq Furqan, Abdul Waheed, Miller Richard
Drs. Solway, Haq, Abdul, and Miller are with Largo Medical Center in Largo, Florida.
Dr. McBride is with Riverside Methodist Hospital in Columbus, Ohio.
J Clin Aesthet Dermatol. 2020 May;13(5):38-43. Epub 2020 May 1.
Previous studies have demonstrated that a whole-food, plant-based (WFPB) diet can aid in the prevention, and in some cases reversal, of some of the leading chronic diseases in the United States. The medical literature on the relationship between diet and disease is steadily growing. Over the last decade, the possible connection between diet and many dermatological conditions has been studied, including skin aging. As patients are increasingly seeking dietary advice from their dermatologist related to preventing and reversing the aging of skin, dermatologists need an evidence-based approach to tackle this challenging topic. This review focuses on dietary factors that contribute to telomere length, a marker for cellular aging. Although various factors contribute to accelerating telomere shortening, this review focuses on dietary factors that contribute to telomere length, specifically gerontotoxins and antioxidants. These can be measured in the blood, making them biomarkers of accelerated cellular skin aging. Included in this discussion is an evidence-based approach to increase the amount of antioxidants and decrease the amount of gerontotoxins in the diet, resulting in healthier skin. A comprehensive MEDLINE (PubMed) literature review search was performed. Keywords used included: and . Inclusion criteria included the above stated keywords and access to full text. A WFPB diet maximizes the antioxidant potential within our cells by providing essential vitamins, including vitamins A, C, and E. It also helps to eliminate harmful carcinogens and gerontotoxins within our bloodstream and has been shown to lengthen telomeres, which prevents cellular damage. Evidence obtained within this literature review supports a WFPB diet for preventing skin aging. .
先前的研究表明,全食物、植物性(WFPB)饮食有助于预防,在某些情况下还能逆转美国一些主要的慢性疾病。关于饮食与疾病关系的医学文献正在稳步增加。在过去十年中,人们研究了饮食与许多皮肤病状况之间的可能联系,包括皮肤老化。随着患者越来越多地向皮肤科医生寻求与预防和逆转皮肤老化相关的饮食建议,皮肤科医生需要一种基于证据的方法来应对这个具有挑战性的话题。这篇综述聚焦于影响端粒长度的饮食因素,端粒长度是细胞老化的一个标志。尽管有多种因素会加速端粒缩短,但这篇综述聚焦于影响端粒长度的饮食因素,特别是衰老毒素和抗氧化剂。这些可以在血液中检测到,使其成为皮肤细胞加速老化的生物标志物。本次讨论包括一种基于证据的方法,即增加饮食中抗氧化剂的含量并减少衰老毒素的含量,从而使皮肤更健康。我们进行了全面的MEDLINE(PubMed)文献综述搜索。使用的关键词包括:以及。纳入标准包括上述关键词以及获取全文。WFPB饮食通过提供必需维生素(包括维生素A、C和E),使我们细胞内的抗氧化潜力最大化。它还有助于清除血液中的有害致癌物和衰老毒素,并且已被证明能延长端粒,从而防止细胞损伤。这篇文献综述中获得的证据支持WFPB饮食可预防皮肤老化。