Khan Dawlat, Saddique Muhammad Umar, Jamshaid Muhammad B, Yousaf Zohaib, Yassin Mohamed A
Internal Medicine, Hamad Medical Corporation, Doha, QAT.
Internal Medicine, Hamad General Hospital, Doha, QAT.
Cureus. 2020 Jul 13;12(7):e9168. doi: 10.7759/cureus.9168.
Adult Still's disease (ASD) is an inflammatory disorder with an unclear etiology. It is a rare disease that was first described more than a century ago. Its common characteristics are daily fevers, arthritis, and skin rash. ASD is diagnosed after excluding infections, malignancies, and connective tissue diseases. It has a female predominance. Classic skin rash and high serum ferritin levels are commonly associated with this condition and help in the diagnosis. Due to a lack of pathognomic clinical and laboratory features, a valid diagnostic criterion, the Yamaguchi criteria, is generally used for the diagnosis. The disease has a good prognosis with appropriate treatment. We present the case of a young gentleman who presented with fever, anemia, and leucocytosis; however, his serum ferritin levels were normal, and there was no typical salmon-colored skin rash. Hyperferritinemia developed later in the disease course, leading to a diagnosis of ASD.
成人斯蒂尔病（ASD）是一种病因不明的炎症性疾病。它是一种罕见疾病，早在一个多世纪前就首次被描述。其常见特征为每日发热、关节炎和皮疹。ASD在排除感染、恶性肿瘤和结缔组织疾病后得以诊断。它以女性居多。典型皮疹和高血清铁蛋白水平通常与该病症相关，有助于诊断。由于缺乏特异性的临床和实验室特征，一般采用有效的诊断标准——山口标准来进行诊断。该病经适当治疗后预后良好。我们报告了一例年轻男性病例，他表现出发热、贫血和白细胞增多；然而，其血清铁蛋白水平正常，且无典型的鲑鱼色皮疹。在病程后期出现了高铁蛋白血症，从而确诊为ASD。
