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脱细胞真皮基质在上肢挽救中的临时应用。

Temporary Use of Acellular Dermal Matrix in Upper Extremity Salvage.

作者信息

Ali Barkat, Wu Jeffrey, Borah Gregory, Wu Eugene

机构信息

Division of Plastic, Reconstructive, Hand and Burn Surgery, University of New Mexico School of Medicine, Albuquerque, N.Mex.

出版信息

Plast Reconstr Surg Glob Open. 2020 Jul 14;8(7):e2965. doi: 10.1097/GOX.0000000000002965. eCollection 2020 Jul.

Abstract

Wound coverage of exposed vascular bypasses after acute limb revascularization may not be immediately possible, while delay may create a hostile environment for the bypass graft. The use of negative-pressure wound therapy may not be possible because of extrinsic compression. Temporary use of acellular dermal matrix can help salvage upper extremity. We present 2 patients with brachial artery transection secondary to blunt trauma, who had revascularization with interposition saphenous vein grafts. We used acellular dermal matrix as temporary coverage for the exposed arterial bypass grafts to allow for patient stabilization, serial debridement, and demarcation of the surrounding tissues before definitive coverage. Additionally, the use of negative-pressure wound therapy caused diminished pulses in the bypass graft, creating the need for reliable temporary coverage. The acellular dermal matrix dressing was left in place until definitive closure was possible. Both patients underwent successful wound coverage with fasciocutaneous flaps without disruption, thrombosis, or infection of the bypass grafts. Follow-up at 6 months demonstrated good healing and excellent function. The use of the acellular dermal matrix provides temporary coverage of vital structures until definitive reconstruction can be performed.

摘要

急性肢体血运重建后,对于暴露的血管搭桥,可能无法立即进行伤口覆盖,而延迟覆盖可能会为搭桥移植物营造不利的环境。由于存在外部压迫,负压伤口治疗可能无法实施。临时使用脱细胞真皮基质有助于挽救上肢。我们报告2例因钝性创伤导致肱动脉横断的患者,他们接受了大隐静脉移植搭桥进行血运重建。我们使用脱细胞真皮基质作为暴露动脉搭桥移植物的临时覆盖物,以便在进行确定性覆盖之前实现患者病情稳定、连续清创以及周围组织的界限划分。此外,负压伤口治疗导致搭桥移植物的脉搏减弱,因此需要可靠的临时覆盖物。脱细胞真皮基质敷料一直保留至能够进行确定性闭合。两名患者均成功采用筋膜皮瓣进行伤口覆盖,搭桥移植物未出现中断、血栓形成或感染。6个月的随访显示愈合良好且功能极佳。脱细胞真皮基质的使用可在进行确定性重建之前为重要结构提供临时覆盖。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0e70/7413757/3d3bcdda7a5e/gox-8-e2965-g001.jpg

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