Department of Ophthalmology, Hongkou Branch of Changhai Hospital, Naval Medical University, Shanghai 200081, China.
Department of Ophthalmology, Eastern Hepatobiliary Surgery Hospital, Naval Medical University, Shanghai 200433, China.
Biomed Res Int. 2020 Jul 30;2020:4723402. doi: 10.1155/2020/4723402. eCollection 2020.
The professional Quality of Life Scale (QLS) can provide a valuable reference for the diagnosis of visual function anomalies. In the present study, we aimed to design a novel QLS to specially quantify the life quality of schoolchildren with nonstrabismic binocular vision anomalies (NSBVAs) in China.
The novel QLS, named QOL-CVF20, was established based on classical vision-related scales and the administration of the questionnaire to 116 schoolchildren with NSBVAs and 100 healthy schoolchildren in China. The diagnostic reference value between QOL-CVF20 and VF-14 was evaluated on the questionnaires to 240 schoolchildren with NSBVAs and 238 healthy schoolchildren.
All the subjects could complete the QOL-CVF20 questionnaires independently. QOL-CVF20 had good structural validity, content validity, and discriminant validity, when it was applied in Chinese schoolchildren. The average score of the NSBVA group was significantly lower than that of the control group (49.0 ± 6.9 vs. 69.7 ± 6.7, respectively; < 0.01). Moreover, the average score of cured NSBVA schoolchildren after treatment (61.8 ± 22.6) was significantly improved ( < 0.01). Receiver operating characteristic curve analysis showed that QOL-CVF20 reflected strong separation between the NSBVA and healthy groups (AUC = 0.901). Meanwhile, QOL-CVF20 could detect individuals with NSBVAs with specificity of 0.847 and sensitivity of 0.846. The critical value of 58.50 in QOL-CVF20 could be effectively applied for quality of life assessment in schoolchildren with NSBVAs.
QOL-CVF20 could quantify the life quality of schoolchildren with NSBVAs and might be served as a valuable reference for early diagnosis and clinical evaluation of NSBVAs.
专业生活质量量表（QLS）可提供有价值的参考，以诊断视觉功能异常。本研究旨在设计一种新型 QLS，专门用于量化中国非斜视性双眼视觉异常（NSBVA）儿童的生活质量。
新型 QLS 命名为 QOL-CVF20，是基于经典的视觉相关量表和对 116 名 NSBVA 患儿和 100 名健康儿童的问卷调查建立的。在对 240 名 NSBVA 患儿和 238 名健康儿童的问卷调查中，评估了 QOL-CVF20 与 VF-14 的诊断参考值。
所有被试者均可独立完成 QOL-CVF20 问卷。在应用于中国儿童时，QOL-CVF20 具有良好的结构效度、内容效度和判别效度。NSBVA 组的平均得分明显低于对照组（分别为 49.0±6.9 和 69.7±6.7， < 0.01）。此外，治疗后治愈的 NSBVA 患儿的平均得分（61.8±22.6）显著提高（ < 0.01）。受试者工作特征曲线分析表明，QOL-CVF20 反映了 NSBVA 组和健康组之间的强烈分离（AUC=0.901）。同时，QOL-CVF20 可以检测出 NSBVAs 个体，特异性为 0.847，敏感性为 0.846。QOL-CVF20 中 58.50 的临界值可有效应用于 NSBVAs 患儿的生活质量评估。
QOL-CVF20 可量化 NSBVA 患儿的生活质量，可能为 NSBVAs 的早期诊断和临床评估提供有价值的参考。
