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疟疾在发热儿童中的流行情况及其社会人口学决定因素——尼日利亚东南部一个发展中社区的基于医院的研究。

Malaria prevalence and its sociodemographic determinants in febrile children - a hospital-based study in a developing community in South-East Nigeria.

机构信息

Department of Pediatrics, Faculty of Medicine, Nnamdi Azikiwe University, Nnewi Campus, Anambra State, Nigeria.

Department of Pediatrics, Nnamdi Azikiwe University Teaching Hospital, Nnewi, Anambra State, Nigeria.

出版信息

J Prev Med Hyg. 2020 Jul 4;61(2):E173-E180. doi: 10.15167/2421-4248/jpmh2020.61.2.1350. eCollection 2020 Jun.

Abstract

BACKGROUND

Malaria remains one of the major contributors of child mortality in many developing countries in Africa. Identifying its determinants will help in prevention and prompt intervention in these settings.

METHODS

This cross-sectional descriptive study was conducted over an eight-month period. It enrolled 382 children who were presented with fever to the children outpatient and emergency unit of a tertiary hospital in South-east Nigeria. A structured questionnaire was used to collect information on socio-demographic factors. Blood film microscopy for malaria and parasite density was done on all subjects that tested positive for malaria.

RESULT

The malaria prevalence rate was 16.7%, 26.7%, 29.9% and 46.2% in children < 5 years, 5 to < 10 years, 10 to < 15 years and 15-17 years respectively. Logistic regression analysis showed that malaria was more prevalent in older children but children under the age of 5 years were more prone to higher parasite density. Also, children of mothers with lower educational attainment, children from families of lower socio-economic class and resident in rural settings had higher likelihood of malaria infection.

CONCLUSIONS

Sustained improvement in strategies to prevent malaria infection is still imperative in children of all ages, especially those under 5 years, children from families of low socio-economic class and those residents in rural communities.

摘要

背景

疟疾仍然是非洲许多发展中国家儿童死亡的主要原因之一。确定其决定因素将有助于在这些环境中预防和及时干预。

方法

这是一项为期八个月的横断面描述性研究。共纳入 382 名发热患儿,他们均来自尼日利亚东南部一家三级医院的儿科门诊和急诊部。使用结构化问卷收集有关社会人口统计学因素的信息。对所有疟疾检测呈阳性的患者进行血涂片显微镜检查以确定疟原虫密度。

结果

年龄<5 岁、5-<10 岁、10-<15 岁和 15-17 岁的儿童疟疾患病率分别为 16.7%、26.7%、29.9%和 46.2%。逻辑回归分析显示,年龄较大的儿童疟疾更为普遍,但年龄<5 岁的儿童更容易出现较高的寄生虫密度。此外,母亲受教育程度较低、社会经济地位较低的家庭的儿童以及居住在农村地区的儿童更有可能感染疟疾。

结论

仍需持续改进预防疟疾感染的策略,这对于所有年龄段的儿童都至关重要,尤其是年龄<5 岁的儿童、社会经济地位较低的家庭的儿童以及居住在农村社区的儿童。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a3da/7419130/8a4cbb7ed0e2/jpmh-2020-02-e173-g001.jpg

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