Ezedudu C E, Ebenebe J C, Chukwuka J O, Ugochukwu E F, Amilo G I, Okorie O I
Niger J Med. 2016 Apr-Jun;25(2):113-18.
Malaria is an infectious disease caused by Plasmodium and transmitted by the bite of an infected female Anopheles mosquito. It continues to be a global challenge with about half of the world's population being at risk of the disease and under–5 children being the most vulnerable.
To determine the prevalence of malaria parasitaemia and some associated symptoms among febrile under-five children presenting at Nnamdi Azikiwe University Teaching Hospital Nnewi, Nigeria.
A total of 200 children under the age of five years were recruited for the study. Data on socio-demographic characteristics and symptoms were collected through interviewer administered questionnaire. They were physically examine and blood sample was collected from each of them. The Blood smear was Giemsa stained and examined microscopically for malaria parasite.
There were 118 males and 82 females, giving a male: female ratio of 1.44:1. Their ages ranged from 3-59 months and the average age was 27+17.49 months. Those in the age range of 12-23 months and 24-35 months constitute the highest number (23%) each. Forty-seven (23.5%) came from the rural area while 153(76.5%) came from the urban area. Average number of days the subjects had fever before presentation were 3.78+1.95 days with a range of 1-30 0 days. Body temperature ranged from 35.9-40.4 C with average of 37.7+0.8oC. Forty (20%) were positive to microscopy. Those in the age range of 47-59 months have the highest prevalence of malaria. Parasite density ranged from 40-136,000/μL with a mean of 18,687.2+3360/μL. All the children who are positive by microcopy had Plasmodium falciparium as the specie causing malaria.
Malaria parasitaemia among these under-5 children is 20%.
疟疾是一种由疟原虫引起的传染病，通过受感染的雌性按蚊叮咬传播。它仍然是一项全球性挑战，全球约一半人口面临感染风险，其中五岁以下儿童最为脆弱。
确定在尼日利亚恩努伊的纳姆迪·阿齐克韦大学教学医院就诊的发热五岁以下儿童中疟疾寄生虫血症的患病率及一些相关症状。
共招募200名五岁以下儿童参与研究。通过访谈问卷收集社会人口学特征和症状数据。对他们进行体格检查，并采集血液样本。血液涂片经吉姆萨染色后显微镜检查疟原虫。
男性118名，女性82名，男女比例为1.44:1。年龄范围为3至59个月，平均年龄为27 + 17.49个月。12至23个月和24至35个月年龄段的儿童人数最多（各占23%）。47名（23.5%）来自农村地区，153名（76.5%）来自城市地区。受试者就诊前发热的平均天数为3.78 + 1.95天，范围为1至30天。体温范围为35.9至40.4摄氏度，平均为37.7 + 0.8摄氏度。40名（20%）显微镜检查呈阳性。47至59个月年龄段的儿童疟疾患病率最高。寄生虫密度范围为40至136,000/微升，平均为18,687.2 + 3360/微升。所有显微镜检查呈阳性的儿童感染的疟原虫种类均为恶性疟原虫。
这些五岁以下儿童中疟疾寄生虫血症的患病率为20%。
