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针对腰神经后支内侧支的外周神经刺激技术治疗慢性下腰痛的综述

A Review of Peripheral Nerve Stimulation Techniques Targeting the Medial Branches of the Lumbar Dorsal Rami in the Treatment of Chronic Low Back Pain.

作者信息

Gilmore Christopher A, Patel Janus, Esebua Lasha-Giorgi, Burchell Michael

机构信息

Carolinas Pain Institute, Winston-Salem, North Carolina, USA.

Center for Clinical Research, Winston-Salem, North Carolina, USA.

出版信息

Pain Med. 2020 Aug 1;21(Suppl 1):S41-S46. doi: 10.1093/pm/pnaa084.

Abstract

OBJECTIVES

The lumbar medial branch nerve has historically been a focus for ablative techniques in the treatment of chronic low back pain (CLBP) of facetogenic origin. Recent developments in the field of neuromodulation have been employed to target these nerves for analgesia and/or functional restoration in broader populations of CLBP patients. The objective of this article was to provide an introductory review of procedural techniques and devices employed for peripheral nerve stimulation (PNS) of the lumbar medial branch of the dorsal ramus for the treatment of CLBP.

METHODS

A literature search via PubMed.gov was performed through September 2019 with key words focusing on peripheral nerve stimulation for chronic low back pain. This was refined to include only those articles that focused specifically on stimulation of the lumbar medial branch of the dorsal ramus. References within selected articles and unpublished data currently in the peer review process were also utilized.

RESULTS

Ninety articles from PubMed.gov were obtained. Two approaches to PNS of the medial branch of the dorsal ramus were identified.

CONCLUSIONS

Our review of the current literature regarding techniques for neuromodulation of the medial branch of the dorsal ramus revealed two dominant methods: a temporarily implanted percutaneous coiled-lead approach and a permanently implanted system. The two techniques share some similarities, such as targeting the medial branch of the dorsal ramus, and also have some differences, such as indwelling time, stimulation parameters, duration of treatment, image guidance, and degrees of invasiveness, but they are both demonstrating promising results in clinical trials.

摘要

目的

从历史上看,腰内侧支神经一直是治疗源于小关节的慢性下腰痛(CLBP)的消融技术的焦点。神经调节领域的最新进展已被用于针对这些神经,以在更广泛的CLBP患者群体中实现镇痛和/或功能恢复。本文的目的是对用于腰神经后支内侧支周围神经刺激(PNS)治疗CLBP的手术技术和设备进行介绍性综述。

方法

通过PubMed.gov进行文献检索,截至2019年9月,关键词聚焦于慢性下腰痛的周围神经刺激。检索范围进一步限定为仅包括那些专门关注腰神经后支内侧支刺激的文章。还利用了所选文章中的参考文献以及目前处于同行评审过程中的未发表数据。

结果

从PubMed.gov获得了90篇文章。确定了两种腰神经后支内侧支PNS的方法。

结论

我们对当前有关腰神经后支内侧支神经调节技术的文献综述揭示了两种主要方法:临时植入的经皮螺旋导线方法和永久植入系统。这两种技术有一些相似之处,例如都针对腰神经后支内侧支,也有一些不同之处,例如留置时间、刺激参数、治疗持续时间、图像引导和侵入程度,但它们在临床试验中均显示出有前景的结果。

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